Currently browsing: Items authored or edited by Katja Rietdorf

Qin, Yi; Ashrafizadeh, Milad; Mongiardini, Vera; Grimaldi, Benedetto; Crea, Francesco; Rietdorf, Katja; Győrffy, Balázs; Klionsky, Daniel J; Ren, Jun; Zhang, Wei and Zhang, Xianbin (2023). Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence. Cancer letters, 570, article no. 216307.

Rietdorf, Katja; Coode, Emily E.; Schulz, Angela; Wibbeler, Eva; Bootman, Martin D. and Ostergaard, John R. (2020). Cardiac pathology in neuronal ceroid lipofuscinoses (NCL): More than a mere co-morbidity. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1866(9), article no. 165643.

• Download Accepted Manuscript (PDF / 1MB)

Masoud, Said; McDonald, Fraser; Bister, Dirk; Kotecki, Claire; Bootman, Martin D. and Rietdorf, Katja (2020). Examining Cardiomyocyte Dysfunction Using Acute Chemical Induction of an Ageing Phenotype. International Journal of Molecular Sciences, 21(1), article no. 197.

• Download Published Version (PDF / 12MB)

Silvestri, Roberto; Pucci, Perla; Venalainen, Erik; Matheou, Chrysanthi; Mather, Rebecca; Chandler, Stephen; Aceto, Romina; Rigas, Sushila; Wang, Yuzhuo; Rietdorf, Katja; Bootman, Martin and Crea, Francesco (2019). T-type calcium channels drive the proliferation of androgen-receptor negative prostate cancer cells. The Prostate, 79(13) pp. 1580–1586.

• Download Accepted Manuscript (PDF / 10MB)

Bittremieux, Mart; La Rovere, Rita M.; Akl, Haidar; Martines, Claudio; Welkenhuyzen, Kirsten; Dubron, Kathia; Baes, Myriam; Janssens, Ann; Vandenberghe, Peter; Laurenti, Luca; Rietdorf, Katja; Morciano, Giampaolo; Pinton, Paolo; Mikoshiba, Katsuhiko; Bootman, Martin D.; Efremov, Dimitar G.; De Smedt, Humbert; Parys, Jan B. and Bultynck, Geert (2019). Constitutive IP₃ signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP₃ receptor disruptor BIRD-2. Cell Death & Differentiation, 26 pp. 531–547.

• Download Published Version (PDF / 4MB)

Coode, Emily; McDonald, Fraser; Bister, Dirk; Bootman, Martin and Rietdorf, Katja (2019). Broken Hearts in Juvenile Dementia: investigating cardiac myocytes in CLN3 disease. In: Gordon Conference on Lysosomal Diseases, 3-8 Mar 2019, Galveston, Texas.

Rietdorf, K.; Coode, E.; McDonald, F.; Bister, D.; Cooper, J.D. and Bootman, M. (2019). Ultrastructural changes in hearts from CLN3 mice. In: Gordon Conference on Lysosomal Diseases, 3-8 Mar 2019, Galveston, Texas.

Rietdorf, Katja; Coode, Emily; MacDonald, Fraser; Bister, Dirk and Bootman, Martin (2018). Broken Hearts in Juvenile Dementia: investigating cardiac myocytes in CLN3 disease. In: International Meeting of the European Calcium Society, 9-13 Sep 2018, Hamburg, Germany.

Rietdorf, Katja; Coode, Emily; MacDonald, Fraser; Bister, Dirk and Bootman, Martin (2018). Broken Hearts in Juvenile Dementia: investigating cardiac myocytes in CLN3 disease. In: NCL 2018, 12-16 Sep 2018, London. UK.

Bootman, Martin D.; Allman, Sarah; Rietdorf, Katja and Bultynck, Geert (2018). Deleterious effects of calcium indicators within cells; an inconvenient truth. Cell Calcium, 73 pp. 82–87.

• Download Accepted Manuscript (PDF / 730kB)
• Download Published Version (PDF / 808kB)

Bootman, Martin D.; Chehab, Tala; Bultynck, Geert; Parys, Jan B. and Rietdorf, Katja (2018). The regulation of autophagy by calcium signals: Do we have a consensus? Cell Calcium, 70 pp. 32–46.

• Request a copy from the author This file is not available for public download

Rietdorf, Katja and MacQueen, Hilary (2017). Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches? British Journal of Pharmacology, 174(20) pp. 3542–3560.

• Download Accepted Manuscript (PDF / 714kB)

Bootman, Martin D. and Rietdorf, Katja (2017). Tissue Specificity: Store-Operated Ca²⁺ Entry in Cardiac Myocytes. In: Groschner, K.; Graier, W. and Romanin, C. eds. Store-Operated Ca²⁺ Entry (SOCE) Pathways. Advances in Experimental Medicine and Biology, 993. Springer, pp. 363–387.

Traore, David; Rietdorf, Katja; Al-Jawad, Naseer and Al-Assam, Hisham (2017). Automatic Hotspots Detection for Intracellular Calcium Analysis in Fluorescence Microscopic Videos. In: Medical Image Understanding and Analysis (Valdés Hernández, M. and González-Castro, V. eds.), Communications in Computer and Information Science, Springer, Cham, pp. 862–873.

• Download Accepted Manuscript (PDF / 855kB)

Masoud, Said; Bootman, Martin D.; McDonald, Fraser; MacQueen, Hilary and Rietdorf, Katja (2016). How does fat cause heart diseases? Effects of epicardial adipocytes on cardiomyocyte signalling and contractility. In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Masoud, Said; Bootman, Martin D.; McDonald, Fraser and Rietdorf, Katja (2016). Can we use chemical-induction of ageing to develop a model of cardiac ageing? In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Sharma, Kumar; Rietdorf, Katja; Proudfoot, Diane; McDonald, Fraser and Bootman, Martin D. (2016). Calcium phosphate crystals found in atherosclerotic plaques induce cytotoxic effects via loss of cellular calcium homeostasis. In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Matheou, Chrysanthi; Chandler, Stephen; Crea, Francesco; Faria, Nuno; Powell, Jonathan; McDonald, Fraser; Rietdorf, Katja and Bootman, Martin D. (2016). Mibefradil; a T-type calcium channel blocker as a potential anti-cancer agent. In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Chehab, Tala; Rietdorf, Katja; Parys, Jan B.; Bultynck, Geert and Bootman, Martin D. (2016). The sources and characteristics of calcium signals determine whether autophagy is up- or downregulated. In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Masoud, Said; Bootman, Martin; McDonald, Fraser and Rietdorf, Katja (2016). Chemically inducing ageing in neonatal rat ventricular myocytes. In: Evolution brings Ca2+ and ATP together to control life and death, 16-17 Mar 2016, Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell.

Rietdorf, Katja; Masoud, Said; McDonald, Fraser and Bootman, Martin (2016). How cells outside the heart can affect the heart beat: The role of pulmonary vein sleeve cells for the development of atrial fibrillation. In: Evolution brings Ca2+ and ATP together to control life and death, 16-17 Mar 2016, Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell.

Schepelmann, M.; Yarova, P. L.; Lopez-Fernandez, I.; Davies, T. S.; Brennan, S. C.; Edwards, P. J.; Aggarwal, A.; Graça, J.; Rietdorf, K.; Matchkov, V.; Fenton, R. A.; Chang, W.; Krssak, M.; Stewart, A.; Broadley, K. J.; Ward, D. T.; Price, S. A..; Edwards, D. H.; Kemp, P. J. and Riccardi, D. (2016). The vascular Ca²⁺-sensing receptor regulates blood vessel tone and blood pressure. American Journal of Physiology - Cell Physiology, 310(3) C193-C204.

Chehab, Tala; Rietdorf, Katja; Parys, Jan B.; Bultynck, Geert and Bootman, Martin (2016). Intracellular calcium: a dual role in autophagy. In: Evolution brings Ca2+ and ATP together to control life and death, 16-17 Mar 2016, Chichley Hall, Newport Pagnell.

Sharma, Kumar; Rietdorf, Katja; Proudfoot, Diane; McDonald, Fraser and Bootman, Martin (2016). Calcium phosphate crystals observed during atherosclerosis have a cytotoxic effect that results in loss of calcium homeostasis. In: Evolution brings Ca2+ and ATP together to control life and death, 16-17 Mar 2016, Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell.

Rietdorf, Katja and MacQueen, Hilary (2015). Interactions between epicardial adipose tissue and cardiomyocytes: results from a 3D co-culture system. In: Pharmacology 2015 (British Pharmacological Society), 15-17 Dec 2015, London.

Chiacchia, M.; Cerutti, C.; Gromnicova, R.; Rietdorf, K.; Romero, I.A. and Bradshaw, D. (2015). Zinc-imidazolate polymers (ZIPs) as a potential carrier to brain capillary endothelial cells. Journal of Materials Chemistry B, 3(46) pp. 9053–9059.

• Download Published Version (PDF / 1MB)

Thul, R.; Rietdorf, K.; Bootman, M. D. and Coombes, S. (2015). Unifying principles of calcium wave propagation — Insights from a three-dimensional model for atrial myocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1853(9) pp. 2131–2143.

• Published Version (PDF) This file is not available for public download

Yarova, Polina L.; Stewart, Alecia L.; Sathish, Venkatachalem; Britt, Rodney D.; Thompson, Michael A.; Lowe, Alexander P. P.; Freeman, Michelle; Aravamudan, Bharathi; Kita, Hirohito; Brennan, Sarah C.; Schepelmann, Martin; Davies, Thomas; Yung, Sun; Cholisoh, Zakky; Kidd, Emma J.; Ford, William R.; Broadley, Kenneth J.; Rietdorf, Katja; Chang, Wenhan; Bin Khayat, Mohd E.; Ward, Donald T.; Corrigan, Christopher J.; T. Ward, Jeremy P.; Kemp, Paul J.; Pabelick, Christina M.; Prakash, Y. S. and Riccardi, Daniela (2015). Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma. Science Translational Medicine, 7(284) 284ra60.

• Download Accepted Manuscript (PDF / 1MB)
• Download Supplementary Material (PDF / 1MB)

Rietdorf, Katja; Masoud, Said; McDonald, Fraser; Sanderson, Michael J. and Bootman, Martin D. (2015). Pulmonary vein sleeve cell excitation–contraction-coupling becomes dysynchronized by spontaneous calcium transients. Biochemical Society Transactions, 43(3) pp. 410–416.

• Published Version (PDF) This file is not available for public download

Rietdorf, Katja; MacQueen, Hilary and Bootman, Martin (2015). How does fat cause heart diseases? Effects of epicardial adipocytes on cardiomyocyte signalling and contractility. In: Heart and Cardiac Muscle Abstracts, article no. PC181.

Masoud, Said; McDonald, Fraser; Bootman, Martin and Rietdorf, Katja (2015). Ageing-induced ultrastructural changes of mitochondria of pulmonary vein sleeve cells. In: Heart and Cardiac Muscle Abstracts, article no. PC183.

Chehab, Tala; Rietdorf, Katja; Parys, Jan; Bultynck, Geert and Bootman, Martin (2015). Inhibition of calcium release from InsP3Rs triggers autophagy. In: Cellular Signalling Abstracts, article no. PC241.

Sharma, G.; Rietdorf, K.; Proudfoot, D.; McDonald, F. and Bootman, M. (2015). Effect of calcium-phosphate crystals on intracellular calcium homeostasis and viability of smooth muscle cell. In: Proceedings of the Physiological Society, article no. PC282.

Chehab, Tala; Rietdorf, Katja; Parys, Jan B.; Bultynck, Geert and Bootman, Martin (2015). Intracellular calcium has a dual role in the regulation of autophagy. In: 6th ECS Workshop: Calcium and Cell Fate, 21-24 Jun 2015, Seillac, France.

Rietdorf, Katja; Masoud, Said; McDonald, Fraser and Bootman, Martin (2015). How cells outside the heart can affect the heart beat: The role of pulmonary vein sleeve cells for the development of atrial fibrillation. In: Gordon Conference on Calcium Signalling, 7-12 Jun 2015, Newry, Maine, USA.

Bootman, Martin D. and Rietdorf, Katja (2015). Atrial myocytes demonstrate the diversity of cardiac calcium signalling. Channels, 9(5) pp. 219–220.

• Download Published Version (PDF / 693kB)

Masoud, Said; Bootman, Martin D.; McDonald, Fraser and Rietdorf, Katja (2014). Spontaneous Ca²⁺ signalling and ultrastructural changes in pulmonary vein sleeve cells during ageing – risk factors for atrial fibrillation? In: Calcium Signalling: The Next Generation, 9-10 Oct 2014, London, UK.

Chehab, Tala; Rietdorf, Katja; Parys, Jan B.; Bultynck, Geert and Bootman, Martin D. (2014). Inhibition of InsP₃ receptor signalling induces autophagy. In: Calcium Signalling: The Next Generation, 9-10 Oct 2014, London, UK.

Rietdorf, Katja; Chehab, Tala; Allman, Sarah and Bootman, Martin D. (2014). Novel improved Ca²⁺ indicator dyes on the market-a comparative study of novel Ca²⁺ indicators with fluo-4. In: Calcium Signalling: The Next Generation, 9-10 Oct 2014, London, UK.

Masoud, Said R.; McDonald, Fraser; Bootman, Martin D. and Rietdorf, Katja (2014). A comparative study into the ultrastructure changes of atrial myocytes, pulmonary vein sleeve cells and ventricular myocytes during ageing. In: Calcium Signalling: The Next Generation, 9-10 Oct 2014, London, UK.

Rietdorf, Katja; Masoud, Said; McDonald, Fraser and Bootman, Martin (2014). Spontaneous Ca2+ signalling and ultrastructural changes in pulmonary vein sleeve cells during ageing – risk factors for atrial fibrillation? In: 13th International Meeting of the European Calcium Society, 13-17 Sep 2014, Aixe-en-Provence, France.

Masoud, Said; Bootman, Martin and Rietdorf, Katja (2014). Spontaneous Ca²⁺ signalling in pulmonary vein sleeve cells increases during ageing. In: Abstracts.

Pitt, Samantha J.; Lam, Andy K. M.; Rietdorf, Katja; Galione, Antony and Sitsapesan, Rebecca (2014). Reconstituted human TPC1 is a proton-permeable ion channel and is activated by NAADP or Ca²⁺. Science Signaling, 7(326), article no. ra46.

Rietdorf, Katja; Bootman, Martin and Sanderson, Michael J. (2014). Spontaneous, pro-arrhythmic calcium signals disrupt electrical pacing in mouse pulmonary vein sleeve cells. PLoS ONE, 9(2), article no. e88649.

• Download Published Version (PDF / 5MB)

Chehab, Tala; Rietdorf, Katja; Parys, Jan; Bultynck, Geert and Bootman, Martin (2014). Inhibition of InsP₃ receptor signalling induces autophagy. In: 13th International Meeting of the European Calcium Society, 13-17 Sep 2014, Aix-en-Provence, France.

Hutter, V.; Murnane, D.; Rietdorf, K.; Fowler, D.; Walton, C. and Bootman, M. (2014). In vitro assessment of alveolar macrophage responses to inhaled particulate medicines. In: Drug Delivery to the Lungs (DDL25), 10-12 Dec 2014, Edinburgh.

Bootman, Martin D.; Rietdorf, Katja; Collins, Tony; Walker, Simon and Sanderson, Michael (2013). Loading fluorescent Ca²⁺ indicators into living cells. Cold Spring Harbor Protocols, 2013(2), article no. pdb.prot072801.

• Download Published Version (PDF / 213kB)

Bootman, Martin D.; Rietdorf, Katja; Collins, Tony; Walker, Simon and Sanderson, Michael (2013). Ca₂₊-sensitive fluorescent dyes and intracellular Ca₂₊ imaging. Cold Spring Harbor Protocols, 2013(2), article no. pdb.top066050.

• Request a copy from the author This file is not available for public download

Bootman, Martin D.; Rietdorf, Katja; Collins, Tony; Walker, Simon and Sanderson, Michael (2013). Converting fluorescence data into Ca²⁺ concentration. Cold Spring Harbor Protocols, 2013(2) pp. 126–129.

• Request a copy from the author This file is not available for public download

Kashir, Junaid; Jones, Celine; Lee, Hoi Chang; Rietdorf, Katja; Nikiforaki, Dimitra; Durrans, Claire; Ruas, Margarida; Tee, Sze Tian; Heindryckx, Bjorn; Galione, Antony; De Sutter, Petra; Fissore, Rafael A.; Parrington, John and Coward, Kevin (2011). Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes. Human Reproduction, 26(12) pp. 3372–87.

• Request a copy from the author This file is not available for public download

Rietdorf, Katja; Funnell, Tim M.; Ruas, Margarida; Heinemann, Jennifer; Parrington, John and Galione, Antony (2011). Two-pore channels form homo- and heterodimers. The Journal of Biological Chemistry, 286(43) pp. 37058–37062.

• Request a copy from the author This file is not available for public download

Pitt, Samantha J.; Funnell, Tim M.; Sitsapesan, Mano; Venturi, Elisa; Rietdorf, Katja; Ruas, Margarida; Ganesan, A.; Gosain, Rajendra; Churchill, Grant C.; Zhu, Michael X.; Parrington, John; Galione, Antony and Sitsapesan, Rebecca (2010). TPC2 is a novel NAADP-sensitive Ca²⁺ release channel, operating as a dual sensor of luminal pH and Ca²⁺. The Journal of Biological Chemistry, 285(45) pp. 35039–46.

• Request a copy from the author This file is not available for public download

Ruas, Margarida; Rietdorf, Katja; Arredouani, Abdelilah; Davis, Lianne C; Lloyd-Evans, Emyr; Koegel, Heidi; Funnell, Timothy M; Morgan, Anthony J; Ward, John A; Watanabe, Keiko; Cheng, Xiaotong; Churchill, Grant C; Zhu, Michael X; Platt, Frances M; Wessel, Gary M; Parrington, John and Galione, Antony (2010). Purified TPC isoforms form NAADP receptors with distinct roles for Ca²⁺ signaling and endolysosomal trafficking. Current Biology, 20(8) pp. 703–709.

• Request a copy from the author This file is not available for public download

Calcraft, Peter J.; Ruas, Margarida; Pan, Zui; Cheng, Xiaotong; Arredouani, Abdelilah; Hao, Xuemei; Tang, Jisen; Rietdorf, Katja; Teboul, Lydia; Chuang, Kai-Ting; Lin, Peihui; Xiao, Rui; Wang, Chunbo; Zhu, Yingmin; Lin, Yakang; Wyatt, Christopher N.; Parrington, John; Ma, Jianjie; Evans, A. Mark; Galione, Antony and Zhu, Michael X. (2009). NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature, 459(7246) pp. 596–600.

• Request a copy from the author This file is not available for public download

Szado, Tania; Vanderheyden, Veerle; Parys, Jan B.; De Smedt, Humbert; Rietdorf, Katja; Kotelevets, Larissa; Chastre, Eric; Khan, Farid; Landegren, Ulf; Söderberg, Ola; Bootman, Martin D. and Roderick, H. Llewelyn (2008). Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca²⁺ release and apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 105(7) pp. 2427–2432.

• Request a copy from the author This file is not available for public download

Kasri, Nael Nadif; Holmes, Anthony M.; Bultynck, Geert; Parys, Jan B.; Bootman, Martin; Rietdorf, Katja; Missiaen, Ludwig; McDonald, Fraser; De Smedt, Humbert; Conway, Stuart J.; Holmes, Andrew B.; Berridge, Michael J. and Roderick, H. Llewelyn (2004). Regulation of InsP₃ receptor activity by neuronal Ca²⁺-binding proteins. The EMBO Journal, 23(2) pp. 312–21.

• Request a copy from the author This file is not available for public download