Currently browsing: Items authored or edited by Francesco Crea https://orcid.org/0000-0002-4903-2973

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Ashrafizaveh, Saeed; Ashrafizadeh, Milad; Zarrabi, Ali; Husmandi, Kiavash; Zabolian, Amirhossein; Shahinozzaman, Md; Aref, Amir Reza; Hamblin, Michael R.; Nabavi, Noushin; Crea, Francesco; Wang, Yuzhuo and Ahn, Kwang Seok (2021). Long non-coding RNAs in the doxorubicin resistance of cancer cells. Cancer Letters, 508 pp. 104–114.

Avan, Amir; Crea, Francesco; Paolicchi, Elisa; Funel, Niccola; Galvani, Elena; Marquez, Victor E; Honeywell, Richard J; Danesi, Romano; Peters, Godefridus J and Giovannetti, Elisa (2012). Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells. Molecular Cancer Therapeutics, 11(8) pp. 1735–1746.

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Clermont, Pier-Luc; Ci, Xinpei; Pandha, Hardev; Wang, Yuzhuo and Crea, Francesco (2019). Treatment-emergent neuroendocrine prostate cancer: molecularly driven clinical guidelines. International Journal of Endocrine Oncology, 6(2), article no. IJE20.

Chandler, Stephen; Gangadharannambiar, Priyadarsini; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushila (2019). Discovery of candidate hub genes in breast cancer. In: New Developments in Breast Cancer Research - From the Lab to the Clinic, 2019 BACR Special Conference, 9-11 Oct 2019, The Sage, Newcastle Gateshead, UK.

Ci, Xinpei; Hao, Jun; Dong, Xin; Choi, Stephen Y.C.; Xue, Hui; Wu, Rebecca; Qu, Sifeng; Gout, Peter W.; Zhang, Fang; Haegert, Anne M.; Fazil, Ladan; Crea, Francesco; Ong, Christopher J.; Zoubedi, Amina; He, Housheng H.; Gleave, Martin E.; Collins, Colin C.; Lin, Dong and Wang, Yuzhuo (2018). Heterochromatin protein 1α mediates development and aggressiveness of neuroendocrine prostate cancer. Cancer Research, 78(10) pp. 2691–2704.

Chandler, Stephen; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushila (2018). Identification of candidate genes that may function in ER- breast cancer. In: BACR Conference: Response and Resistance in Cancer Therapy, 10-12 Sep 2018, University of Kent, Canterbury.

Chandler, Stephen; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushilaben (2017). Identification of putative functional genes in breast and other cancers with potentially shared aetiology. In: The Human Genome in Healthcare, 23-24 Nov 2017, The Royal Society, London, UK.

Crea, Francesco; Venalainen, Erik; Ci, Xinpei; Cheng, Hongwei; Pikor, Larissa; Parolia, Abhijit; Xue, Hui; Nur Saidy, Nur Ridzwan; Lin, Dong; Lam, Wan; Collins, Colin and Wang, Yuzhuo (2016). The role of epigenetics and long noncoding RNA MIAT in neuroendocrine prostate cancer. Epigenomics, 8(5) pp. 721–731.

Crea, Francesco; Quagliata, Luca; Michael, Agnieszka; Liu, Hui Hsuan; Frumento, Paolo; Azad, Arun A.; Xue, Hui; Pikor, Larissa; Wathaiki, Akira; Morant, Rudolf; Castori-Eppenberger, Serenella; Wang, Yuwei; Parolia, Abhijit; Lennox, Kim A.; Lam, Wan L.; Gleave, Martin; Chi, Kim N.; Pandha, Hardev; Wang, Yuzhuo and Helgason, Cheryl D. (2016). Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression. Molecular Oncology, 10(5) pp. 693–703.

Clermont, Pier-Luc; Crea, Francesco; Chiang, Yan Ting; Lin, Dong; Zhang, Amy; Wang, James Z. L.; Parolia, Abhijit; Wu, Rebecca; Xue, Hui; Wang, Yuwei; Ding, Jiarui; Thu, Kelsie L.; Lam, Wan L.; Shah, Sohrab P.; Collins, Colin C.; Wang, Yuzhuo and Helgason, Cheryl D. (2016). Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer. Clinical Epigenetics, 8, article no. 16.

Crea, Francesco; Di Paolo, Antonello; Liu, Hui Hsuan; Polillo, Marialuisa; Clermont, Pier-Luc; Guerrini, Francesca; Ciabatti, Elena; Ricci, Federica; Baratè, Claudia; Fontanelli, Giulia; Barsotti, Sara; Morganti, Riccardo; Danesi, Romano; Wang, Yuzhuo; Petrini, Mario; Galimberti, Sara and Helgason, Cheryl D. (2015). Polycomb genes are associated with response to imatinib in chronic myeloid leukemia. Epigenomics, 7(5) pp. 757–765.

Clermont, Pier-Luc; Lin, Dong; Crea, Francesco; Wu, Rebecca; Xue, Hui; Wang, Yuwei; Thu, Kelsie L; Lam, Wan L; Collins, Colin C; Wang, Yuzhuo and Helgason, Cheryl D (2015). Polycomb-mediated silencing in neuroendocrine prostate cancer. Clinical Epigenetics, 7(40)

Crea, Francesco; Nur Saidy, Nur Ridzwan; Collins, Colin C. and Wang, Yuzhuo (2015). The epigenetic/noncoding origin of tumor dormancy. Trends in molecular medicine, 21(4) pp. 206–11.

Clermont, P-L; Sun, L; Crea, F; Thu, K L; Zhang, A; Parolia, A; Lam, W L and Helgason, C D (2014). Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role. British Journal of Cancer, 111(8) pp. 1663–1672.

Crea, Francesco; Clermont, Pier-Luc; Mai, Antonello and Helgason, Cheryl D. (2014). Histone modifications, stem cells and prostate cancer. Current Pharmaceutical Design, 20(11) pp. 1687–1697.

Crea, Francesco; Clermont, Pier Luc; Parolia, Abhijit; Wang, Yuzhuo and Helgason, Cheryl D. (2014). The non-coding transcriptome as a dynamic regulator of cancer metastasis. Cancer Metastasis Reviews, 33(1) pp. 1–16.

Crea, Francesco; Watahiki, Akira; Quagliata, Luca; Xue, Hui; Pikor, Larissa; Parolia, Abhijit; Wang, Yuwei; Lin, Dong; Lam, Wan L.; Farrar, William L.; Isogai, Takao; Morant, Rudolf; Castori-Eppenberger, Serenella; Chi, Kim N.; Wang, Yuzhuo and Helgason, Cheryl D. (2014). Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer. Oncotarget, 5(3) pp. 764–774.

Crea, Francesco and Fornaro, Lorenzo (2014). Genome-epigenome interactions: the Polycomb paradox. Epigenomics, 6(1) pp. 5–7.

Crea, F.; Sun, L.; Pikor, L.; Frumento, P.; Lam, W. L. and Helgason, C. D. (2013). Mutational analysis of Polycomb genes in solid tumours identifies PHC3 amplification as a possible cancer-driving genetic alteration. British Journal of Cancer, 109(6) pp. 1699–1702.

Crea, Francesco; Fornaro, Lorenzo; Bocci, Guido; Sun, Lei; Farrar, William L.; Falcone, Alfredo and Danesi, Romano (2012). EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis. Cancer and Metastasis reviews, 31(3) pp. 753–761.

Crea, Francesco; Sun, Lei; Mai, Antonello; Chiang, Yan Ting; Farrar, William L.; Danesi, Romano and Helgason, Cheryl D. (2012). The emerging role of histone lysine demethylases in prostate cancer. Molecular Cancer, 11, article no. 52.

Crea, Francesco; Paolicchi, Elisa; Marquez, Victor E. and Danesi, Romano (2012). Polycomb genes and cancer: time for clinical application? Critical Reviews in Oncology/Hematology, 83(2) pp. 184–193.

Crea, F.; Fornaro, L.; Paolicchi, E.; Masi, G.; Frumento, P.; Loupakis, F.; Salvatore, L.; Cremolini, C.; Schirripa, M.; Graziano, F.; Ronzoni, M.; Ricci, V.; Farrar, W. L.; Falcone, A. and Danesi, R. (2012). An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO, 23(5) pp. 1207–13.

Crea, Francesco; Nobili, Stefania; Paolicchi, Elisa; Perrone, Gabriele; Napoli, Cristina; Landini, Ida; Danesi, Romano and Mini, Enrico (2011). Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies. Drug Resistance Updates, 14(6) pp. 280–296.

Crea, Francesco; Fornaro, Lorenzo; Masi, Gianluca; Falcone, Alfredo; Danesi, Romano and Farrar, William (2011). Faithful markers of circulating cancer stem cells: is CD133 sufficient for validation in clinics? Journal of Clinical Oncology, 29(25) pp. 3487–3488.

Crea, Francesco; Hurt, Elaine M.; Mathews, Lesley A.; Cabarcas, Stephanie M.; Sun, Lei; Marquez, Victor E.; Danesi, Romano and Farrar, William L. (2011). Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer. Molecular Cancer, 10, article no. 40.

Crea, Francesco; Duhagon Serrat, Maria A.; Hurt, Elaine M.; Thomas, Suneetha B.; Danesi, Romano and Farrar, William L. (2011). BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer. International Journal of Cancer, 128(8) pp. 1946–1954.

Crea, Francesco (2011). EZH2 and cancer stem cells: fact or fiction? Epigenomics, 3(2) pp. 127–128.

Crea, Francesco; Hurt, Elaine M. and Farrar, William L. (2010). Clinical significance of Polycomb gene expression in brain tumors. Molecular Cancer, 9, article no. 265.

Crea, Francesco; Mathews, Lesley A.; Farrar, William L. and Hurt, Elaine M. (2009). Targeting prostate cancer stem cells. Anti-cancer agents in medicinal chemistry, 9(10) pp. 1105–1113.

Crea, Francesco; Giovannetti, Elisa; Zinzani, Pier Luigi and Danesi, Romano (2009). Pharmacologic rationale for early G-CSF prophylaxis in cancer patients and role of pharmacogenetics in treatment optimization. Critical Reviews in Oncology/Hematology, 72(1) pp. 21–44.

Crea, Francesco; Danesi, Romano and Farrar, William L. (2009). Cancer stem cell epigenetics and chemoresistance. Epigenomics, 1(1) pp. 63–79.

Chandler, Stephen; Gangadharannambiar, Priyadarsini; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushila Discovery of candidate long non-coding RNAs as biomarkers and treatment targets for prostate cancer. In: NEPC 2019. Treatment-emergent neuroendocrine prostate cancer: clinical relevance and molecular pathogenesis., 25 Jun 2019, The Open University, Milton Keynes, UK.

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Duhagon, M. A.; Crea, F.; Danesi, R. and Farrar, W. L. (2013). Embryonic stem cell pathways and chemotherapy response: an unexplored route. Annals of Oncology, 24(2) pp. 558–559.

Donzella, Valentina and Crea, Francesco (2011). Optical biosensors to analyze novel biomarkers in oncology. Journal of Biophotonics, 4(6) pp. 442–452.

Danesi, Romano; Pasqualetti, Giuseppe; Giovannetti, Elisa; Crea, Francesco; Altavilla, Giuseppe; Del Tacca, Mario and Rosell, Rafael (2009). Pharmacogenomics in non-small-cell lung cancer chemotherapy. Advanced Drug Delivery Reviews, 61(5) pp. 408–417.

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Fornaro, Lorenzo; Vivaldi, Caterina; Lin, Dong; Xue, Hui; Falcone, Alfredo; Wang, Yuzhuo; Crea, Francesco and Bootman, Martin D. (2017). Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation. PLoS ONE, 12(8), article no. e0182818.

Fornaro, Lorenzo; Faviana, Pinuccia; De Gregorio, Veronica; Vivaldi, Caterina; Paolicchi, Elisa; Masi, Gianluca; Loupakis, Fotios; Sensi, Elisa; Lupi, Cristiana; Fontanini, Garbriella; Wang, Yuzhuo; Danesi, Romano; Falcone, Alfredo and Crea, Francesco (2015). Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer. BMC Cancer, 15, article no. 874.

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Juan-Larrea, Naiara; Mather, Rebecca; Romero, Ignacio A.; Sibson, Nicola R. and Crea, Francesco (2018). The role of long non-coding RNAs in breast cancer dissemination to the brain. In: CRUK brain tumour conference, 1-3 May 2018, London.

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Lavik, Andrew R.; McColl, Karen S.; Lemos, Fernanda O.; Kerkhofs, Martijn; Zhong, Fei; Harr, Michael; Schlatzer, Daniela; Hamada, Kozo; Mikoshiba, Katsuhiko; Crea, Francesco; Bultynck, Geert; Bootman, Martin D.; Parys, Jan B. and Distelhorst, Clark W. (2022). A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca2+ signalling through IP3 receptors. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1869(4), article no. 119206.

Latarani, Maryam; Pucci, Perla; Roig-Carles, David; Eccleston, Mark; Xue, Hui; Hawkes, Cheryl; Rigas, Sushila; Wang, Yuzhuo and Crea, Francesco (2020). EZH2 as a therapeutic target for aggressive prostate cancer. In: Crick Cancer Research Symposium, iPoster, 5-6 Oct 2020, The Francis Crick Institute and Virtual.

Lin, Dong; Dong, Xin; Wang, Kendric; Wyatt, Alexander W.; Crea, Francesco; Xue, Hui; Wang, Yuwei; Wu, Rebecca; Bell, Robert H.; Haegert, Anne; Brahmbhatt, Sonal; Hurtado-Coll, Antonio; Gout, Peter W.; Fazli, Ladan; Gleave, Martin E.; Collins, Colin C. and Wang, Yuzhuo (2015). Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer. Oncotarget, 6(3) pp. 1806–1820.

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Mather, Rebecca L.; Parolia, Abhijit; Carson, Sandra E.; Venalainen, Erik; Roig-Carles, David; Jaber, Mustapha; Chu, Shih‐Chun; Alborelli, Ilaria; Wu, Rebecca; Lin, Dong; Nabavi, Noushin; Jachetti, Elena; Colombo, Mario P.; Xue, Hui; Pucci, Perla; Ci, Xinpei; Hawkes, Cheryl; Li, Yinglei; Pandha, Hardev; Ulitsky, Igor; Marconett, Crystal; Quagliata, Luca; Jiang, Wei; Romero, Ignacio A; Wang, Yuzhuo and Crea, Francesco (2021). The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms. Molecular Oncology, 15(7) pp. 1921–1941.

Mather, Rebecca; Andrews, Henry; Pandha, Hardev; Jachetti, Elena; Micallef, Jake; Wang, Yuzhuo and Crea, Francesco (2020). The Open University’s first one day symposium on treatment-emergent neuroendocrine prostate cancer. In: Future Oncology, Future Medicine.

Mather, Rebecca L.; Venalainen, Erik; Pucci, Perla; Lin, Dong; Xue, Hui; Wang, Yuzhuo and Crea, Francesco (2017). The long non-coding RNA NEAR1 promotes neuroendocrine prostate cancer cell proliferation and survival. In: 3rd International Cancer Symposium, Cancer Research Center of Lyon (CRCL), 25-27 Sep 2017, Lyon, France.

Matheou, Chrysanthi; Chandler, Stephen; Crea, Francesco; Faria, Nuno; Powell, Jonathan; McDonald, Fraser; Rietdorf, Katja and Bootman, Martin D. (2016). Mibefradil; a T-type calcium channel blocker as a potential anti-cancer agent. In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Mathews, Lesley A.; Crea, Francesco and Farrar, W. L. (2009). Epigenetic gene regulation in stem cells and correlation to cancer. Differentiation, 78(1) pp. 1–17.

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Nabavi, Noushin; Saidy, Nur Ridzwan Nur; Venalainen, Erik; Haegert, Anne; Parolia, Abhijit; Xue, Hui; Wang, Yuwei; Wu, Rebecca; Dong, Xin; Collins, Colin; Crea, Francesco and Wang, Yuzhuo (2017). miR-100-5p inhibition induces apoptosis in dormant prostate cancer cells and prevents the emergence of castration-resistant prostate cancer. Scientific reports, 7(1), article no. 4079.

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Pucci, Perla; Crea, Francesco; Alborelli, Ilaria; Quagliata, Luca; Bootman, Martin; Rigas, Sushilaben; Romero, Ignacio and Wang, Yuzhuo (2020). Long non-coding RNAs are key players in Prostate cancer tumorigenesis and drug resistance. In: 27th Annual PCF Scientific Retreat Virtual Poster Session, 20-23 Oct 2020, Virtual, Morressier.

Parolia, Abhijit; Venalainen, Erik; Xue, Hui; Mather, Rebecca; Lin, Dong; Wu, Rebecca; Pucci, Perla; Rogalski, Jason; Evans, Joseph; Feng, Felix; Collins, Colin; Wang, Yuzhuo and Crea, Francesco (2019). The long non-coding RNA HORAS5 mediates castration-resistant prostate cancer survival by activating the androgen receptor transcriptional program. Molecular Oncology, 13(5) pp. 1121–1136.

Pucci, Perla; Rescigno, Pasquale; Sumanasuriya, Semini; de Bono, Johann and Crea, Francesco (2018). Hypoxia and Noncoding RNAs in Taxane Resistance. Trends in Pharmacological Sciences, 39(8) pp. 695–709.

Pucci, Perla; Venalainen, Erik; Mather, Rebecca; Xue, Hui; Rigas, Sushila; Romero, Ignacio A; Wang, Yuzho and Crea, Francesco (2017). Identification of a long non-coding RNA that mediates response to therapy in castration-resistant prostate cancer. In: 3rd International Cancer Symposium, 25-27 Sep 2017, Lyon, France.

Paolicchi, E.; Vivaldi, C.; De Gregorio, V.; Crea, F.; Fornaro, L.; Masi, G.; Loupakis, F.; Graziano, F.; Ronzoni, M.; Ricci, V.; Falcone, A. and Danesi, R. (2016). Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients. Oncology, 91(5) pp. 283–288.

Paolicchi, Elisa; Crea, Francesco; Farrar, William L.; Green, Jeffrey E. and Danesi, Romano (2013). Histone lysine demethylases in breast cancer. Critical Reviews in Oncology/Hematology, 86(2) pp. 97–103.

Pastina, Ilaria; Giovannetti, Elisa; Chioni, Aldo; Sissung, Tristan M.; Crea, Francesco; Orlandini, Cinzia; Price, Douglas K.; Cianci, Claudia; Figg, William D.; Ricci, Sergio and Danesi, Romano (2010). Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients. BMC Cancer, 10, article no. 511.

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Roig-Carles, David; Jackson, Holly; Loveson, Katie F.; Mackay, Alan; Mather, Rebecca; Waters, Ella; Manzo, Massimiliano; Alborelli, Ilaria; Golding, Jon; Jones, Chris; Fillmore, Helen L. and Crea, Francesco (2021). The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation. International Journal of Molecular Sciences, 22(17), article no. 9165.

Ricciardi, S.; Mey, V.; Nannizzi, S.; Pasqualetti, G.; Crea, F.; Del Tacca, M. and Danesi, R. (2010). Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells. Chemotherapy, 56(4) pp. 303–312.

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Wang, Yong; Wang, Yu; Ci, Xinpei; Choi, Stephen Y C; Crea, Francesco; Lin, Dong and Wang, Yuzhuo (2021). Molecular events in neuroendocrine prostate cancer development. Nature Reviews Urology (Early Access).

Watahiki, Akira; Macfarlane, Robyn J.; Gleave, Martin E.; Crea, Francesco; Wang, Yuzhuo; Helgason, Cheryl D. and Chi, Kim N. (2013). Plasma miRNAs as biomarkers to identify patients with castration-resistant metastatic prostate cancer. International Journal of Molecular Sciences, 14(4) pp. 7757–7770.

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