Currently browsing: Items authored or edited by Daniel Berwick

Granno, Simone; Nixon-Abell, Jonathon; Berwick, Daniel; Tosh, Justin; Heaton, George; Almudimeegh, Sultan; Nagda, Zenisha; Rain, Jean-Christophe; Zanda, Manuela; Plagnol, Vincent; Tybulewicz, Victor L. J.; Cleverley, Karen; Wiseman, Frances K.; Fisher, Elizabeth M. C. and Harvey, Kirsten (2019). Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific Reports, 9, article no. 7322.

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Berwick, Daniel C.; Heaton, George R.; Azeggagh, Sonia and Harvey, Kirsten (2019). LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same. Molecular neurodegeneration, 14, article no. 49.

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Cararo-Lopes, Marina Minto; Mazucanti, Caio Henrique Yokoyama; Scavone, Cristoforo; Kawamoto, Elisa Mitiko and Berwick, Daniel Charles (2017). The relevance of α-KLOTHO to the central nervous system: Some key questions. Ageing Research Reviews, 36 pp. 137–148.

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Azeggagh, Sonia; Adan, Abdullahi; Needs, Sarah; Murphy, Kerry; Allman, Sarah and Berwick, Daniel (2017). A comprehensive "Disease-in-a-Dish" approach to Parkinson's Disease. In: British Neuroscience Association - 2017 Festival of Neuroscience, 10-13 Apr 2017, Birmingham, United Kingdom.

Berwick, Daniel C.; Javaheri, Behzad; Wetzel, Andrea; Hopkinson, Mark; Nixon-Abell, Jonathon; Granno, Simone; Pitsillides, Andrew A. and Harvey, Kirsten (2017). Pathogenic LRRK2 variants are gain-of function mutations that enhance LRRK2-mediated repression of β-catenin signaling. Molecular Neurodegeneration, 12, article no. 9.

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Needs, Sarah; Adan, Abdullahi; Berwick, Daniel; Bootman, Martin and Allman, Sarah (2016). CRISPR /Cas9 gene editing to study N-glycanase1 deficiency. In: 3rd BioProNET Annual Scientific Symposium, 19-20 Oct 2016, East Midlands Conference Centre, Nottingham, UK.

Nixon-Abell, Jonathon; Berwick, Daniel C.; Granno, Simone; Spain, Victoria A.; Blackstone, Craig and Harvey, Kirsten (2016). Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity. Frontiers in Molecular Neuroscience, 9, article no. 18.

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Berwick, Daniel C. and Harvey, Kirsten (2014). The regulation and deregulation of Wnt signaling by PARK genes in health and disease. Journal of Molecular Cell Biology, 6(1) pp. 3–12.

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Law, Bernard M. H.; Spain, Victoria A.; Leinster, Veronica H. L.; Chia, Ruth; Beilina, Alexandra; Cho, Hyun J.; Taymans, Jean-Marc; Urban, Mary K.; Sancho, Rosa M.; Blanca Ramírez, Marian; Biskup, Saskia; Baekelandt, Veerle; Cai, Huaibin; Cookson, Mark R.; Berwick, Daniel C. and Harvey, Kirsten (2014). A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation. Journal of Biological Chemistry, 289(2) pp. 895–908.

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Berwick, Daniel C. and Harvey, Kirsten (2013). LRRK2: an éminence grise of Wnt-mediated neurogenesis? Frontiers in Cellular Neuroscience, 7, article no. 82.

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Berwick, Daniel C. and Harvey, Kirsten (2012). LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6. Human Molecular Genetics, 21(22) pp. 4966–4979.

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Berwick, Daniel C. and Harvey, Kirsten (2012). The importance of Wnt signalling for neurodegeneration in Parkinson's disease. Biochemical Society Transactions, 40(5) pp. 1123–1128.

Berwick, Daniel C. and Harvey, Kirsten (2011). LRRK2 signaling pathways: the key to unlocking neurodegeneration? Trends in Cell Biology, 21(5) pp. 257–65.

Berwick, Daniel C.; Diss, James K. J.; Budhram-Mahadeo, Vishwanie S. and Latchman, David S. (2010). A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction. The Journal of Biological Chemistry, 285(20) pp. 15286–15295.

Berwick, Daniel C.; Calissano, Mattia; Corness, Jacqueline D.; Cook, Simon J. and Latchman, David S. (2009). Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation. Brain research, 1256 pp. 8–18.

Welsh, G. I.; Hers, I.; Berwick, D. C.; Dell, G.; Wherlock, M.; Birkin, R.; Leney, S. and Tavaré, J. M. (2005). Role of protein kinase B in insulin-regulated glucose uptake. Biochemical Society Transactions, 33(2) pp. 346–349.

Franke, Thomas F. and Berwick, Daniel C. (2005). PI3K, PTEN and Akt. In: Dufour, Jean-Francois; Clavien, Pierre-Alain; Trautwein, Christian and Graf, Rolf eds. Signaling Pathways in Liver Diseases. Berlin, Heidelberg, New York: Springer-Verlag, pp. 239–257.

Berwick, Daniel C.; Dell, Ghislaine C.; Welsh, Gavin I.; Heesom, Kate J.; Hers, Ingeborg; Fletcher, Laura M.; Cooke, Frank T. and Tavaré, Jeremy M. (2004). Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles. Journal of cell science, 117 pp. 5985–5993.

Berwick, Daniel C. and Tavaré, Jeremy M. (2004). Identifying protein kinase substrates: hunting for the organ-grinder's monkeys. Trends in Biochemical Sciences, 29(5) pp. 227–232.

Berwick, Daniel C.; Hers, Ingeborg; Heesom, Kate J.; Moule, S. Kelly and Tavare, Jeremy M. (2002). The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes. Journal of Biological Chemistry, 277(37) pp. 33895–33900.