Currently browsing: Items authored or edited by Carol Midgley

Lu, Tiangong; Goh, Aik Wye; Yu, Mingfeng; Adams, Julian; Lam, Frankie; Teo, Theodosia; Li, Peng; Noll, Ben; Zhong, Longjin; Diab, Sarah; Chahrour, Osama; Hu, Anran; Abbas, Abdullahi Y,; Liu, Xiangrui; Huang, Shiliang; Sumby, Christopher J.; Milne, Robert; Midgley, Carol and Wang, Shudong (2014). Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities. Journal of Medicinal Chemistry, 57(6) pp. 2275–2291.

Chahrour, Osama; Abdalla, Ashraf; Lam, Frankie; Midgley, Carol and Wang, Shudong (2011). Synthesis and biological evaluation of benzyl styrylsulfonyl derivatives as potent anticancer mitotic inhibitors. Bioorganic and Medicinal Chemistry Letters, 21(10) pp. 3066–3069.

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Higgins, Julie; Midgley, Carol A.; Bergh, Anna-Maria; Bell, Sandra M.; Askham, Jonathan M.; Roberts, Emma; Binns, Ruth K.; Sharif, Saghira M.; Bennett, Christopher; Glover, David M.; Woods, C. Geoffrey; MorrisonBond, Ewan E. and Bond, Jacquelyn (2010). Human ASPM participates in spindle organisation, spindle orientation and cytokinesis. BMC Cell Biology, 11 p. 85.

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Wang, Shudong; Griffiths, Gary; Midgley, Carol A.; Barnett, Anna L.; Cooper, Michael; Grabarek, Joanna; Ingram, Laura; Jackson, Wayne; Kontopidis, George; McClue, Steven J.; McInnes, Campbell; McLachan, Janice; Meades, Christopher; Mezna, Mokdad; Stuart, Iain; Thomas, Mark P.; Zheleva, Daniella I.; Lane, David P.; Jackson, Robert C.; Glover, David M.; Blake, David G. and Fischer, Peter M. (2010). Discovery and characterization of 2-Anilino-4-(Thiazol-5-yl)Pyrimidine transcriptional CDK inhibitors as anticancer agents. Chemistry and Biology, 17(10) pp. 1111–1121.

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Wang, Shudong; Midgley, Carol A.; Scaërou, Frederic; Grabarek, Joanna B.; Griffiths, Gary; Jackson, Wayne; Kontopidis, George; McClue, Steven J.; McInnes, Campbell; Meades, Christopher; Mezna, Mokdad; Plater, Andy; Stuart, Iain; Thomas, Mark P.; Wood, Gavin; Clarke, Rosemary G.; Blake, David G.; Zheleva, Daniella I.; Lane, David P.; Jackson, Robert C.; Glover, David M. and Fischer, Peter M. (2010). Discovery of N-Phenyl-4-(thiazol-5-yl)pyrimidin-2-amine Aurora Kinase Inhibitors. Journal of Medicinal Chemistry, 53(11) pp. 4367–4378.

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McInnes, Campbell; Mazumdar, Aveek; Mezna, Mokdad; Meades, Christopher; Midgley, Carol; Scaerou, Fred; Carpenter, Lee; Mackenzie, Mairi; Taylor, Paul; Walkinshaw, Malcolm; Fischer, Peter M. and Glover, David (2006). Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance. Nature Chemical Biology, 2(11) pp. 608–617.

Wang, Shudong; Wood, Gavin; Meades, Christopher; Griffiths, Gary; Midgley, Carol; McNae, Ian; McInnes, Campbell; Anderson, Sian; Jackson, Wayne; Mezna, Mokdad; Yuill, Rhoda; Walkinshaw, Malcolm and Fischer, Peter M. (2004). Synthesis and biological activity of 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine CDK inhibitors. Bioorganic and Medicinal Chemistry Letters, 14(16) pp. 4237–4240.

Wang, Shudong; Meades, Christopher; Wood, Gavin; Osnowski, Andrew; Anderson, Sian; Yuill, Rhoda; Thomas, Mark; Mezna, Mokdad; Jackson, Wayne; Midgley, Carol; Griffiths, Gary; Fleming, Ian; Green, Simon; McNae, Ian; Wu, Su-Ying; McInnes, Campbell; Zheleva, Daniella; Walkinshaw, Malcolm D. and Fischer, Peter M. (2004). 2-Anilino-4-(thiazol-5-yl)pyrimidine CDK Inhibitors: Synthesis, SAR Analysis, X-ray Crystallography, and Biological Activity. Journal of Medicinal Chemistry, 47(7) pp. 1662–1675.

Liu, Wei-Li; Midgley, Carol; Stephen, Charles; Saville, Mark and Lane, David P. (2001). Biological significance of a small highly conserved region in the N terminus of the p53 tumour suppressor protein. Journal of Molecular Biology, 313(4) pp. 711–731.

DEAK, PETER; FRENZ, LISA; GLOVER, DAVID and Midgley, Carol (2005). Cell cycle progression proteins. CYCLACEL LTD, US2005227243.

GLOVER, DAVID; BELL, GRAHAM; FRENZ, LISA and Midgley, Carol (2004). Cell cycle progression proteins. CYCLACEL LTD (GB); GLOVER DAVID (GB); BELL GRAHAM (GB); FRENZ LISA (GB); MIDGLEY CAROL (GB), WO2004063362.

Deak, Peter; Glover, David and Midgley, Carol (2003). Cell Cycle Progression proteins. Cyclacel Ltd, US2003152945.