Browse by Partner Institution Thesis

Number of items at this level: 99.
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MPhilTo Top

Doubi, Melpomenie Guissouegou (2024). The Role of Pin1 in innate immunity. MPhil thesis The Open University.

Ivanova, Neli (2007). Predicting Function and Structure using Bioinformatics Protocols:Study of the Intracellular Regions of the Jagged and Delta Protein Families. MPhil thesis The Open University.

Sims, Jason (2013). Stability of a Translocated Chromosome in Chronological Ageing Yeast. MPhil thesis The Open University.

Triolo, Gianluca (2020). Proteomic Analysis of Merkel Cell Polyomavirus. MPhil thesis The Open University.

PhDTo Top

Aguilar Peña, Claudio Andrés (2003). The quorum sensing system and the stationary phase RpoS sigma factor of the onion pathogen Burkholderia cepacia Gv 1 type strain, ATCC 25416. PhD thesis The Open University.

Akinyi, Maureen Veronica (2015). Characterizing RNA Targets of TDP-43. PhD thesis The Open University.

Albornoz, Amelina Andrea (2014). The role of TIA-1 as a cellular restriction factor for tick-borne encephalitis virus infection. PhD thesis The Open University.

Ali, Hashim (2015). Cellular TRIM33 ubiquitin ligase restricts HIV-1 infection by targeting viral integrase. PhD thesis The Open University.

Altun, Burçin (2015). Microbial Biodegradation of Lignocellulose for Ethanol Production. PhD thesis The Open University.

Arnak, Remigiusz (2012). Genome's architecture in the maintenance of chromosomes' identity during BIT - bridge induced translocations in Saccharomyces cerevisiae. PhD thesis The Open University.

Arrisi Mercado, Pablo (2004). Molecular basis of the human ApoAII exon 3 splicing. PhD thesis The Open University.

Asensio, Cristian Jorge Alejandro (2003). Mycobacterium avium infection-induced changes in cytosolic protein phosphorylation of THP-1 macrophages. PhD thesis The Open University.

Bajpai, Sailesh (2010). Analysis of the human RECQ1 helicase function in cells. PhD thesis The Open University.

Basukala, Om (2019). The Role of HPV E7 in Maintenance of Cell Transformation. PhD thesis The Open University.

Baykal, Betül (2015). Quantitative Analysis of the Proteomic Response of Human Tumor Cell Lines to Sirtinol. PhD thesis The Open University.

Bhuvanagiri, Madhuri (2009). Exon definition in neurofibromatosis type 1 pre mRNA processing. PhD thesis The Open University.

Bočkor, Luka (2015). Characterization of a new mouse model for Crigler-Najjar Syndrome Type 1 and possible therapeutic approaches. PhD thesis The Open University.

Bonin, Serena (2001). Analysis of expression profiles of signalling and regulatory pathways in tumour tissues. PhD thesis The Open University.

Boon, Siaw Shi (2014). Phospho-Regulation of Cancer Causing Human Papillomavirus (HPV) E6 Oncoproteins. PhD thesis The Open University.

Bortolotti, Francescaa (2015). An innovative selection strategy for the identification of novel cytokines inducing cardiac protection and mesenchymal stromal cell survival after myocardial infarction. PhD thesis The Open University.

Braga, Luca (2017). Identification and Characterization of MicroRNAs Modulating Cardiac Hypertrophy. PhD thesis The Open University.

Brindisi, Antonia (2006). Characterization of CFTR exon 9 splicing inhibition mediated by pre-mRNA interaction with TDP43. PhD thesis The Open University.

Camparini, Luca (2019). Growth Differentiation Factor 11 and Myostatin: Mechanism and Therapeutic Role in Cardiovascular Diseases. PhD thesis The Open University.

Cappelli, Sara (2019). Role of TDP-43 and hnRNP Proteins in the Regulation of Different RNA Targets. PhD thesis The Open University.

Caputo Galarce, Valentina (2003). Implementation of an extrachromosomal system for the detection of novel DNA double strand break repair genes in S. cerevisiae. PhD thesis The Open University.

Čemažar, Maša (2003). Oxidative Folding of a Cystine Knot Protein: the Amaranthus α-amylase Inhibitor. PhD thesis The Open University.

Cesarec, Mia (2017). Hepatitis C Virus NS5A Targets the Nucleosome Assembly Protein NAP1L1 to Control the Interferon Response. PhD thesis The Open University.

Chiavelli, Chiara (2015). Characterization of the Molecular Mechanism of the Tissue-Specific and Developmentally Regulated Alternative Splicing of SCN9A Exon 5. PhD thesis The Open University.

Colombin, Martina (2013). The role of UBZ1 in PCNA-dependent DNA damage response. PhD thesis The Open University.

Costantini, Silvia Elvira (2007). Characterization of the macromolecular interactions of the key NHEJ components. PhD thesis The Open University.

Coutinho, Bruna Gonçalves (2014). Quorum Sensing and Plant-Induced Gene Expression in the Novel Group of Plant Beneficial and Environmental Burkholderia. PhD thesis The Open University.

Çevik, Recep Emrah (2014). Hepatitis C virus NS5A modulates the nucleosome assembly protein NSP1L1 to control the cellular innate immunity response. PhD thesis The Open University.

D'Ambrogio, Andrea (2008). Structural and functional studies on TDP-43 : a novel splicing regulator. PhD thesis The Open University.

De Conti, Laura (2007). Mechanism of pre-mRNA splicing regulation : selection of 5' splice sites. PhD thesis The Open University.

de Sabbata, Giulia (2014). The protein phosphatase activity of PTEN regulates p53 phosphorylation. PhD thesis The Open University.

Dos Santos Olivera, Renato Antonio (2010). Antibiotics in mycobacteria-macrophage system and its consequences at both microorganism and host cell level. PhD thesis The Open University.

Falanga, Alessia (2012). Compensatory Relationship Between Exonic Splicing Enhancer, Splice Site and Protein Function. PhD thesis The Open University.

Ferluga, Sara (2008). Studies on the Inter-Cellular Communication Mechanisms in the Rice Bacterial Pathogens Xanthomonas oryzae pv. oryzae and Pseudomonas fuscovaginae. PhD thesis The Open University.

Gammoh, Noor (2007). Regulation of HPV 16-E7 by E2, Phosphorylation and the Proteasome. PhD thesis The Open University.

Ganti, Ktaki (2015). Interaction of the human papillomavirus E6 oncoproteins with the cellular proteolytic and transport machinery. PhD thesis The Open University.

Gbadamosi, Monsurat Titi (2021). Characterization of the Futsch/MAP1B Rescue of Locomotion Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis. PhD thesis The Open University.

Godena, Vinay Kumar (2010). Molecular characterization of TDP-43/TBPH functions in vivo using Drosophila Melanogaster. PhD thesis The Open University.

Goina, Elisa (2008). Role and Mechanism of Action of Exonic Splicing Regulatory Sequences. PhD thesis The Open University.

Guarnaccia, Corrado (2001). Interaction of RGG and HTH motifs with nucleic acids: a study with rationally designed synthetic and recombinant polypeptides. PhD thesis The Open University.

Haque, Ariful (2010). Characterisation of a Composite Exonic Regulatory Element of Splicing (CERES) in CFTR Exon 12: Functional Properties and Evolutionary Constraints. PhD thesis The Open University.

Herzog, Jerem (2015). Investigation of dysregulation of TDP43 and its role in molecular pathology. PhD thesis The Open University.

Holodkov, Nikola (2018). Glutamic acid metabolism alterations, causes and consequences in ALS. PhD thesis The Open University.

Joshi, Sonal (2024). Tim4: A New Sentinel in Tumor Immune Surveillance. PhD thesis The Open University.

Kaján, László (2005). Development of computer-based methods for the prediction of protein structure and function. PhD thesis The Open University.

Kazungu, Yvette (2020). A Role of Unfolded Protein Response in the Cellular Response to Flavivirus Infection. PhD thesis The Open University.

Kranjec, Christian (2013). Contribution of Human Papillomavirus E6 PDZ-Binding Activity to Virus-Induced Pathogenesis. PhD thesis The Open University.

Kula, Anna (2009). Identification and characterization of protein complexes involved in HIV-1 RNA biogenesis, processing and export. PhD thesis The Open University.

Lewandowska, Marzena Anna (2006). Functional studies on the intronic splicing processing elements in the ataxia telangiectasia mutated gene. PhD thesis The Open University.

Lucic, Bojana (2011). Understanding the structural basis of the human RECQ1 helicase function. PhD thesis The Open University.

Mancardi, Sabrina (2001). Characterization of endothelial cells of lymphatic vessels. PhD thesis The Open University.

Marcucci, Roberto (2007). Insights into the mechanism of the splice site selection by regulatory elements containing G runs. PhD thesis The Open University.

Marro, Martin (2001). Pathological consequences of beta-adducin gene deletion in mice. PhD thesis The Open University.

Martinelli, Valentina (2010). Characterisation and functional analysis of proteins involved in neuromuscular diseases and cardiomyopathy. PhD thesis The Open University.

Mattioli, Chiara (2013). Role of spliceosome and microprocessor complex in the processing of Splice site Overlapping pri-miR-34b. PhD thesis The Open University.

Mora Cardenas, Erick Noe (2020). Optimization of Recombinant Flavivirus Antigens for Infection Serology: Towards Syndrome-Based Multiplex Tests. PhD thesis The Open University.

Moretti, Federico Andrea (2007). FN-EDA domain knock-in and knock-out mice, as a model for the study of the hepatic fibronectin (FN) functions. PhD thesis The Open University.

Morgan, Marcus (2011). Annotation and function of conserved 3'UTRs in humans. PhD thesis The Open University.

Narayan, Nisha (2008). Functional Regulation of the Discs Large Tumour Suppressor by Phosphorylation. PhD thesis The Open University.

Nascimento Alves, Lais (2022). Antagonism of the Integrated Stress Response By Tick-Borne Encephalitis Virus. PhD thesis The Open University.

Nedeljković, Mirjana (2012). Non-Canonical cis-Acting Elements Regulating Polyadenylation of the Beta-Adducin Pre-mRNA. PhD thesis The Open University.

Noel, Pawan (2010). Discrete DNA Integration Events During Bridge-Induced Translocation Generate Partial Chromosomal Deletions and Differential Aneuploidy in Saccharomyces cerevisiae. PhD thesis The Open University.

Palacios Fábrega, José́ Alejandro (2007). Interaction between the DNA repair machinery and the adeno-associated virus (AAV) : vector transduction and site-specific integration. PhD thesis The Open University.

Paron, Francesca (2021). TDP-43 Aberrant Phosphorylation in Amyotrophic Lateral Sclerosis (ALS) and in Niemann-Pick type C (NPC) Disease. PhD thesis The Open University.

Passoni, Monica (2011). Dinucleotide TG Repeats and 5' Splice Site Definition. PhD thesis The Open University.

Pastor, Tibor (2010). Identification and molecular characterization of an intronic regulatory element involved in aberrant splicing of ATM. PhD thesis The Open University.

Patel, Hitendra Kumar (2014). Quorum sensing and virulence studies in two emerging Pseudomonas phytopathogens; Pseudomonas fuscovaginae and Pseuomonas syringae pv. actinidiae. PhD thesis The Open University.

Petris, Gianluca (2013). The Mechanism of ER to Cytosol Retrotranslocation of Proteins Targeted to ERAD (ER Associated Degradation). PhD thesis The Open University.

Popuri, Venkateswarlu (2008). Structural and biochemical characterization of the human RECQ1 helicase. PhD thesis The Open University.

Prosdocimo, Giulia (2018). Development of the Clinical Application of miRNA with Proregenerative Effect on the Heart. PhD thesis The Open University.

Quadri, Zainuddin (2015). Investigating TDP-43 aggregation in cell-based and animal-based models. PhD thesis The Open University.

Rawat, Vipin Singh (2018). DNA Damage Induction by Bilirubin Induced Oxidative Stress and Activation of DNA Repair Pathways by Bilirubin. PhD thesis The Open University.

Ring, Nadja Anneliese Ruth (2017). Functional Identification of MicroRNAs Counteracting Cellular Senescence. PhD thesis The Open University.

Rogalska, Malgorzata Ewa (2014). Determinants involved in splicing correction mediated by exon specific U1 snRNAs. PhD thesis The Open University.

Romano, Valentina (2014). Characterization of TDP-43 aggregation using a cellular model based on its C-terminal Q/N rich region. PhD thesis The Open University.

Rossi, Fabio (2012). Functional characterization of WRNIP1. PhD thesis The Open University.

Saxena, Himanshi (2024). Liver-directed gene targeting as a potential therapy for Fabry Disease. PhD thesis The Open University.

Slon Campos, Jose Luis (2017). Evaluation of a Tetravalent DNA Vaccine against Dengue: Integrating Biochemical Studies on Dengue Virus Envelope Protein to a Domain-Based Antigen Design. PhD thesis The Open University.

Sterlinko Grm, Helena (2005). Dissection of the Interplay Between HPV E6 and Its Cellular and Viral Targets. PhD thesis The Open University.

Strah, Nina (2019). The Role of Muscular TDP-43 in Neuromuscular Junction Development and Progress of ALS. PhD thesis The Open University.

Šušnjar, Urša (2022). Comparative Analysis of TDP-43-Controlled RNA Processing in Neuronal and Muscle Cells in Mouse and Human. PhD thesis The Open University.

Švab, Živa (2021). Identification and Molecular Characterization of Process Relevant MicroRNAs in Chinese Hamster Ovary (CHO) Cells: CHO Optimization for the Production of Recombinant Proteins of Pharmaceutical Interest. PhD thesis The Open University.

Thatte, Jayashree (2018). The Role of Post Translational Modification in Regulating Human Papillomavirus (HPV) E6 Functions. PhD thesis The Open University.

Tomaić, Vjekoslav (2009). The Role of the Ubiquitin Proteasome Pathway in Papillomavirus Pathogenicity. PhD thesis The Open University.

Torrini, Consuelo (2018). Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules. PhD thesis The Open University.

Trejo Cerro, Oscar (2023). Regulation of the Human Papillomavirus E7 Oncoprotein. PhD thesis The Open University.

Vats, Arushi (2021). Understanding the Biology of HPV E6 Oncoprotein in Cervical Cancer. PhD thesis The Open University.

Vega, Carla Vanessa Sarabia (2020). Towards an Understanding of the Evolution of the HPV E6 PDZ Binding Motif. PhD thesis The Open University.

Vicidomini, Antonio (2024). Development of AAV-based liver gene therapies for stable correction of Ornithine Transcarbamylase Deficiency. PhD thesis The Open University.

Vodret, Simone (2016). Neonatal Hyperbilirubinemia: in vivo Characterization of Mechanisms of Bilirubin Neurotoxicity and Pharmacological Treatments. PhD thesis International Centre for Genetic Engineering and Biotechnology.

Vu, Diem My (2021). Screening the Ubiquitination Components Essential for Cardiomyocyte Proliferation and Cardiac Regeneration. PhD thesis The Open University.

Wang, Yixu (2023). Bacterial cell-cell inter-species signaling in the plant endosphere. PhD thesis The Open University.

Zago, Paula (2009). Investigating multiple roles of RNA secondary structure, trans-acting factors and evolutionary pressure on the splicing regulation of fibronectin EDA exon. PhD thesis The Open University.

Zubovic, Lorena (2011). Characterization of the mechanisms behind the alternative splicing of the mutually exclusive exons 18N and 18A in the sodium channel gene SCN8A and mutually exclusive exons 5N and 5A in the soldium channel gene SCN9A. PhD thesis The Open University.

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