Browse by Partner Institution Thesis

Number of items at this level: 90.
Generated on Thu Jan 23 11:47:02 2025 GMT.

2025To Top

Pontis, Francesca (2025). Role of Plasma Extracellular Vesicles in Lung Cancer Pre-Metastatic Niche Formation. Doctor of Philosophy (PhD) thesis The Open University.

2024To Top

Cascini, Caterina (2024). The transcription factor ZEB1 shapes osteosarcoma aggressiveness by affecting tumour cell differentiation and stemness features. Doctor of Philosophy (PhD) thesis The Open University.

Cosentino, Giulia (2024). Tissue miRNAs as a Tool to Predict and Improve Benefit From Trastuzumab. Doctor of Philosophy (PhD) thesis The Open University.

Ghislanzoni, Silvia (2024). Investigation of Therapy-Induced Senescent Cancer Cell Phenotypes with Mass Spectrometry and Non-Linear Optical Microscopy. Doctor of Philosophy (PhD) thesis The Open University.

Gioscio, Eliana (2024). Development of Global and Local Spatial Descriptors of the Radiotherapy Dose: a tool to improve the search for dose-toxicity relationships in hollow organs. Doctor of Philosophy (PhD) thesis The Open University.

2023To Top

Serafini, Mara Serena (2023). Immunotherapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma: biological landscape and prognostic biomarkers to improve patients' stratification. Doctor of Philosophy (PhD) thesis The Open University.

Sulsenti, Roberta (2023). Intracellular Osteopontin Controls the Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer. Doctor of Philosophy (PhD) thesis The Open University.

2022To Top

Perrone, Milena (2022). Role of Transcription Factor Atf3 in the Bone Marrow Microenvironment During Breast Cancer Development: A Response Marker or an Active Player of Tumourigenesis? Doctor of Philosophy (PhD) thesis The Open University.

Vandoni, Giulia (2022). Role of Diet and Gut Microbiome on Clinical Outcomes in Patients with Advanced Melanoma. Doctor of Philosophy (PhD) thesis The Open University.

Varinelli, Luca (2022). Decellularised Normal and Tumour Scaffolds for Cancer Organoid Cultures as a Model of Colorectal Peritoneal Metastases. Doctor of Philosophy (PhD) thesis The Open University.

2021To Top

Bassani, Barbara (2021). Role of CD40 and Zeb1 in Shaping Normal and Leukemic Bone Marrow Niche. Doctor of Philosophy (PhD) thesis The Open University.

Di Cosimo, Serena (2021). Liquid Biopsy in Breast Cancer: Molecular Characterization and Support to Clinical Management. Doctor of Philosophy (PhD) thesis The Open University.

Rizzello, Celeste (2021). Osteopontin protects from autoimmunity-driven diffuse large B cell lymphoma development. Doctor of Philosophy (PhD) thesis The Open University.

Talarico, Giovanna (2021). Extracellular Matrix Regulation of Breast Cancer Immune Microenvironment. Doctor of Philosophy (PhD) thesis The Open University.

2020To Top

Di Modica, Martina (2020). Gut Microbiota and Trastuzumab Response in HER2- Positive Breast Cancer. Doctor of Philosophy (PhD) thesis The Open University.

Doldi, Valentina (2020). Stromal Gene Signatures as Source of Targets for Drug-Repositioning and Prognostic Biomarkers in Prostate Cancer. Doctor of Philosophy (PhD) thesis The Open University.

Enriquez, Claudia (2020). Adenocarcinoma-neuroendocrine Transition Of Androgen Resistant PCa Depends On SPARC Down-regulation In Stromal Accessory Cells. Doctor of Philosophy (PhD) thesis The Open University.

Reduzzi, Carolina (2020). Analysis of Single Circulating Tumor Cells (CTCs) to Infer Phenotype and Genome Changes in Response to Therapeutic Pressures in Biliary Tract Cancer. Doctor of Philosophy (PhD) thesis The Open University.

Shahaj, Eriomina (2020). Modulation of Immune Checkpoints by Tumour Extracellular Vesicles. Doctor of Philosophy (PhD) thesis The Open University.

2019To Top

Arrighetti, Noemi (2019). RNA Interference Approaches and Assessment of New Delivery Systems to Target Heparanase in Soft-tissue Sarcomas. Doctor of Philosophy (PhD) thesis The Open University.

2018To Top

Castagnoli, Lorenzo (2018). Role Of d16HER2 Splice Variant In Breast Cancer Stem Cells. Doctor of Philosophy (PhD) thesis The Open University.

Dugo, Matteo (2018). Dissecting Melanoma Heterogeneity by Integrative Genomic Analysis for Tailored Anti-Cancer Therapy. Doctor of Philosophy (PhD) thesis The Open University.

El Bezawy, Rihan (2018). Dissecting the Role of microRNAs in the Radiation Response of Human Prostate Cancer. Doctor of Philosophy (PhD) thesis The Open University.

Majorini, Maria Teresa (2018). Investigating the Role of the Inhibitor of Apoptosis Proteins (IAPs) in Metastasis Formation. Doctor of Philosophy (PhD) thesis The Open University.

Nicoletti, Roberta (2018). Deciphering The Role of miR-506 in Ovarian Cancer Drug Sensitivity. Doctor of Philosophy (PhD) thesis The Open University.

Tuccitto, Alessandra (2018). pH Regulatory Molecules In The Tumour Microenvironment: Modulators Of Aggressiveness And Immune Profile Of Human Hepatocellular Carcinoma. Doctor of Philosophy (PhD) thesis The Open University.

2017To Top

Cetti, Elena (2017). Identification and Characterization of Potential Novel Targets in Thyroid Carcinoma: Evidence of Non-Oncogene Addiction Unveiling Tumor Cell Vulnerabilities. Doctor of Philosophy (PhD) thesis The Open University.

Fina, Emanuela (2017). Biological and Clinical Significance of Circulating Tumor Cells in Breast Cancer. Doctor of Philosophy (PhD) thesis The Open University.

Maiorana, Maria Valeria (2017). Analysis Of The Effects Of Metformin Administered Alone Or In Combined Treatments In Colorectal Cancer. Doctor of Philosophy (PhD) thesis The Open University.

Triulzi, Tiziana (2017). Identification of Markers to Predict Benefit from Trastuzumab Treatment. Doctor of Philosophy (PhD) thesis The Open University.

2016To Top

D'Ippolito, Elvira (2016). Role of miRNAs in the tumour-mediated vascularisation of triple negative breast cancer. Doctor of Philosophy (PhD) thesis The Open University.

Magni, Martina (2016). Functional characterization of the human protein deleted in breast cancer 1 (DBC1) involvement in the DNA damage response. Doctor of Philosophy (PhD) thesis The Open University.

Minna, Emanuela (2016). MiRNA deregulation in thyroid carcinogenesis :"in vitro" models to study molecular mechanisms and functional effects. Doctor of Philosophy (PhD) thesis The Open University.

Tomirotti, Andrea Massimiliano (2016). Identification of Early Biomarkers of Neoplastic Transformation in Mouse Tumour Models of Breast Carcinogenesis. Doctor of Philosophy (PhD) thesis The Open University.

2015To Top

Bernareggi, Davide (2015). Conversion of AFRA FAB into a fully human monoclonal antibody directed against folate receptor alpha: in vitro and in vivo studies. Doctor of Philosophy (PhD) thesis The Open University.

Ciceri, Sara (2015). Molecular characterization of Wilms tumour. Doctor of Philosophy (PhD) thesis The Open University.

Dassano, Alice (2015). Expression networks and effectors of genetic susceptibility to lung cancer in mice. Doctor of Philosophy (PhD) thesis The Open University.

Ghedini, Gaia Cristina (2015). Role of Δ16HER2 splice variant in the aggressiveness and response of HER2-positive breast cancer to drugs targeting HER2 receptor. Doctor of Philosophy (PhD) thesis The Open University.

Kuchuk, Olga Valentynivna (2015). Interference of pH regulators as an immunomodulating therapeutic strategy for liver cancer. Doctor of Philosophy (PhD) thesis The Open University.

Lecis, Daniele (2015). Inhibitors of Apoptosis Proteins (IAPs) as Targets for Anti-Cancer Treatment. Doctor of Philosophy (PhD) thesis The Open University.

Profumo, Valentina (2015). The functional role of miR-205 in normal and malignant human prostate : a role for miR-205 host gene in prostate epithelial cell differentiation. Doctor of Philosophy (PhD) thesis The Open University.

Sasso, Marianna (2015). CDCP1 as a biomarker of aggressive phenotype in triple negative breast cancer. Doctor of Philosophy (PhD) thesis The Open University.

Torselli, Ilaria (2015). The influence of tumor microenvironment on osteosarcoma progression. Doctor of Philosophy (PhD) thesis The Open University.

2014To Top

Rigoni, Alice (2014). Mast cells at the interface between external challenges and immune regulation in colitis and colorectal cancer. Doctor of Philosophy (PhD) thesis The Open University.

Santangelo, Alessandra (2014). SPARC, a matricellular protein that protects cancer from therapy. Doctor of Philosophy (PhD) thesis The Open University.

2013To Top

Boeri, Mattia (2013). Exploring the role of microRNAs in early lung cancer. Doctor of Philosophy (PhD) thesis The Open University.

Catucci, Irene (2013). Identification of low-penetrance alleles, genetic modifiers and mutation analysis in familial breast cancer cases. Doctor of Philosophy (PhD) thesis The Open University.

2012To Top

Anania, Maria Chiara (2012). Role of genes differentially expressed in thyroid carcinogenesis. Doctor of Philosophy (PhD) thesis The Open University.

Burocchi, Alessia (2012). Modulation of regulatory T cell suppression in tumors through OX40. Doctor of Philosophy (PhD) thesis The Open University.

Cossa, Giacomo (2012). Modulation of sensitivity to platinum compounds in ovarian carcinoma cell systems. Doctor of Philosophy (PhD) thesis The Open University.

Piovan, Claudia (2012). MicroRNAs in breast tissue biology and disease : involvement in development and tumourigenesis processes. Doctor of Philosophy (PhD) thesis The Open University.

Vizioli, Maria Grazia (2012). Role of Oncogene-Induced Senescence in Thyroid Carcinogenesis. Doctor of Philosophy (PhD) thesis The Open University.

2011To Top

Bortolomai, Ileana (2011). Identification and Characterization of Tumour Initiating Cells From Gynaecological Malignancies. Doctor of Philosophy (PhD) thesis The Open University.

Colombo, Francesca (2011). Functional analyses of genetic elements associated with lung cancer. Doctor of Philosophy (PhD) thesis The Open University.

Crippa, Elisabetta (2011). Identification of miRNA target gene pairs involved in hereditary breast cancer. Doctor of Philosophy (PhD) thesis The Open University.

Frullanti, Elisa (2011). Genome-wide identification of functional polymorphisms modulating individual risk and prognosis of lung cancer. Doctor of Philosophy (PhD) thesis The Open University.

Passafaro, Alfonso Luca (2011). Role of SPARC in inflammation and cancer. Doctor of Philosophy (PhD) thesis The Open University.

Perego, Michela (2011). Phenotypical and functional studies on putative cancer stem cells of human melanoma. Doctor of Philosophy (PhD) thesis The Open University.

Zappasodi, Roberta (2011). Active and Adoptive Immunotherapy in Indolent Lymphoproliferative Diseases. Doctor of Philosophy (PhD) thesis The Open University.

2010To Top

Bertolini, Giulia (2010). Isolation and characterization of lung cancer initiating cells. Doctor of Philosophy (PhD) thesis The Open University.

Gandellini, Paolo (2010). Expression and function of miR-21 and miR-205 in prostate cancer. Doctor of Philosophy (PhD) thesis The Open University.

Iorio, Marilena V (2010). Role of microRNAs in human breast and ovarian cancer. Doctor of Philosophy (PhD) thesis The Open University.

2009To Top

Alessandrini, Isabella (2009). Manipulating macrophage activities in tumor microenvironment. Doctor of Philosophy (PhD) thesis The Open University.

Casati, Chiara (2009). Human LAG-3 (lymphocyte activation gene-3) molecule activity on dendritic cells and the promotion of type-1 tumour-specific immunity. Doctor of Philosophy (PhD) thesis The Open University.

De Cecco, Loris (2009). Breast cancer gene expression profiling for a molecular classification and clinical outcome. Doctor of Philosophy (PhD) thesis The Open University.

Vallacchi, Viviana (2009). CCN3/NOV matricellular protein regulates adhesion and dissemination in melanoma. Doctor of Philosophy (PhD) thesis The Open University.

2008To Top

De Filippo, Annamaria (2008). Receptor-dependency, immunological properties and functional mediated interaction of heat shock protein Gp96 on human blood plasmacytoid dendritic cells. Doctor of Philosophy (PhD) thesis The Open University.

Mortarino, Mimosa (2008). Different approaches for the selection and development of PSMA-specific SCFVS for the treatment of prostate carcinoma. Doctor of Philosophy (PhD) thesis The Open University.

Pennati, Marzia (2008). Strategies for surviving down-regulation : effects on tumour cell growth potential and chemosensitivity profile. Doctor of Philosophy (PhD) thesis The Open University.

Piconese, Silvia (2008). Manipulation of CD4⁺ CD25⁺ regulatory T cells in cancer immunotherapy through co-stimulatory molecules. Doctor of Philosophy (PhD) thesis The Open University.

2007To Top

Buscemi, Giacomo (2007). Analysis of Chk2, ATM, NBS1, three proteins involved in the cellular response to DNA damage. Doctor of Philosophy (PhD) thesis The Open University.

Galbiati, Federica (2007). Functional characterization of allelic variants of pulmonary adenoma susceptibility 1 (Pas1) genes for their cancer modifier activity. Doctor of Philosophy (PhD) thesis The Open University.

Petti, Carlotta (2007). Identification of molecular targets of oncogenic NRAs and BRAF involved in regulation of melanoma cell proliferation. Doctor of Philosophy (PhD) thesis The Open University.

Sala, Elisa (2007). Analysis and inhibition of oncogenic RET-dependent signalling. Doctor of Philosophy (PhD) thesis The Open University.

2006To Top

Huber, Veronica Barbara (2006). Expression of pro-apoptotic molecules by tumour cells and their roles in tumour immune escape. Doctor of Philosophy (PhD) thesis The Open University.

Magistroni, Vera (2006). Role of BCR/ABL kinase domain mutations and epigenetic BIM silencing as mechanisms of protection from apoptosis in haematological malignancies. Doctor of Philosophy (PhD) thesis The Open University.

Zannini, Laura (2006). Analysis of the functional domains of the cell cycle checkpoint kinase CHK2. Doctor of Philosophy (PhD) thesis The Open University.

2005To Top

Guiducci, Cristiana (2005). Redirecting dendritic cells and macrophages towards tumor rejection. Doctor of Philosophy (PhD) thesis The Open University.

Massa, Chiara (2005). Immunological properties of a secreted form of murine inducible HSP70. Doctor of Philosophy (PhD) thesis The Open University.

Roccato, Emanuela (2005). Role of TFG sequences in the activation of the TRK-T3 oncogene. Doctor of Philosophy (PhD) thesis The Open University.

2004To Top

Carniti, Cristiana (2004). Study of the RET receptor dysfunctions caused by mutations associated with human neoplastic disorders and developmental diseases. Doctor of Philosophy (PhD) thesis The Open University.

Spinola, Monica (2004). Population based analysis of candidate genes affecting lung adenocarcinoma progression. The Open University.

2003To Top

Renkvist, Nicolina (2003). Functional characterisation of the T cell mediated anti-tumour response in a melanoma patient : identification of a HLA-DRβ1*10011 restricted unique antigen. Doctor of Philosophy (PhD) thesis The Open University.

Turatti, Fabio (2003). The design and validation of a novel fully human chimeric immune receptor to redirect transduced effectors to antigen expressing tumour cells. The Open University.

Zaffaroni, Daniela (2003). Mapping of skin cancer susceptibility loci in mice. The Open University.

2002To Top

Gri, Giorgia (2002). The role of interferon-gamma and other cytokines in the antitumor activity of interleukin-12. The Open University.

Nardini, Elena (2002). Characterization of genetic events involving IgH switch regions in gastric low-grade MALT lymphomas and B-CLL. Doctor of Philosophy (PhD) thesis The Open University.

2001To Top

Colella, Gennaro Giovanni Domenico (2001). Molecular analysis of DNA damage induced by a novel trinuclear platinum complex (BBR 3464). Doctor of Philosophy (PhD) thesis The Open University.

Sfondrini, Lucia (2001). Enhancement of anti-tumour immunity by transduction with a Mycobacterium tuberculosis gene. Doctor of Philosophy (PhD) thesis The Open University.

1994To Top

Bianchi, Alexander Peter (1994). Studies of volatile organic compounds in the water and sediments of a British estuary : Southampton Water. Doctor of Philosophy (PhD) thesis The Open University.

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