What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes

Monteford, Jorge; Bilverstone, Terry W.; Ingle, Patrick; Philip, Sheryl; Kuehne, Sarah A. and Minton, Nigel P. (2021). What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes. Anaerobe, 71, article no. 102422.

DOI: https://doi.org/10.1016/j.anaerobe.2021.102422

Abstract

Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20291 is taken into account in research outcomes.

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