The production of pig preimplantation embryos in vitro: Current progress and future prospects

Fowler, Katie E.; Mandawala, Anjali A.; Griffin, Darren K.; Walling, Grant A. and Harvey, Simon C. (2018). The production of pig preimplantation embryos in vitro: Current progress and future prospects. Reproductive Biology, 18(3) pp. 203–211.

DOI: https://doi.org/10.1016/j.repbio.2018.07.001

Abstract

Human assisted reproductive technology procedures are routinely performed in clinics globally, and some of these approaches are now common in other mammals such as cattle. This is currently not the case in pigs. Given that the global population is expected to increase by over two billion people between now and 2050, the demand for meat will also undoubtedly increase. With this in mind, a more sustainable way to produce livestock; increasing productivity and implementing methods that will lead to faster genetic selection, is imperative. The establishment of routine and production scale pig embryo in vitro production could be a solution to this problem. Producers would be able to increase the overall number of offspring born, animal transportation would be more straightforward and in vitro produced embryos could be produced from the gametes of selected elite. Here we review the most recent developments in pig embryology, outline the current barriers and key challenges that exist, and outline research priorities to surmount these difficulties.