Protection against Ab induces memory loss by tripeptide D-Arg-L-Glu-D-Arg

Mileusnic, R.; Lancashire, C.; Clark, J. and Rose, S. (2007). Protection against Ab induces memory loss by tripeptide D-Arg-L-Glu-D-Arg. In: Iqbal, I.; Wingblat, B. and Avila, J. eds. Alzheimer's Disease: New Advances. Medimond International Proceedings. Bologna, Italy: Medimond, pp. 435–438.

URL: http://www.monduzzi.com/proceedings/moreinfo/20060...

Abstract

The diastomeric (D/L) form of acetylated tripeptide RER protects against A-beta induced memory loss for a passive avoidance task in young chicks and enhances retention for a weak version of the task when injected peripherally up to 12 hr prior to training. The tripeptide readilly crosses the blood-brain barrier, binds to membrane receptor sites in the brain and is whithout adverse effets on general behaviour. RER-related peptides may forma basis for a therapetic agent in the early stages of AD

Viewing alternatives

Look up in Google Scholar
No digital document available to download for this item

Item Actions

Export

About

CORE (COnnecting REpositories)