Chemical genetics

Shuker, David (2007). Chemical genetics. Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, 103 pp. 165–173.

DOI: https://doi.org/10.1039/b614414b

URL: http://www.rsc.org/Publishing/Journals/OC/article....

Abstract

This report covers some highlights in chemical genetics published during 2006. Significant advances have been made in the development of diversity-oriented synthesis to make new molecules with natural product-like skeletal diversity. The use of small molecules to interact with specific pathways in order to understand biological mechanisms and to identify new drug targets is also a main focus of this report.

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