Electrochemistry of Eugenol and its Metabolism on a Bare Screen-Printed Electrode

Vasiliadou, Rafaela (2018). Electrochemistry of Eugenol and its Metabolism on a Bare Screen-Printed Electrode. Athens Journal of Sciences, 5(1) pp. 39–52.

DOI: https://doi.org/10.30958/ajs.5-1-3

Abstract

Eugenol is an essential oil widely used in pharmaceutical and food industry. However, the metabolism of eugenol leads to the formation of a highly reactive phenoxyl radical that can induce toxicity with macromolecules. Herein, a simple and a cost-effective methodology was described for the mimicry of eugenol metabolism. Electrochemical measurements were recorded on bare screen-printed electrodes (SPEs) and the generated metabolites were collected and detected by electrospray ionization (ESI)/Mass spectrometry (MS). The reactive intermediate was successfully formed illustrating a cheaper alternative towards the mimicry of human metabolism.

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