×
Copy the page URI to the clipboard
Jones, Raymond C.F.; Berthelot, Didier J.C. and Iley, James N.
(2007).
DOI: https://doi.org/10.3998/ark.5550190.0008.b07
URL: http://www.arkat-usa.org/get-file/23153/
Abstract
Amino acids carrying aromatic carbo- and heterocycles in the side chain, such as naphthyl-, biphenyl- and pyridylalanines, have been prepared by alkylation of a glycine enolate with a haloalkyl carbocycle or heterocycle, with enantiomeric excess up to 87% using the ephedrine amide protocol.