Monitoring biomineralization of biomaterials in vivo

Mehrban, N. and Bowen, J. (2016). Monitoring biomineralization of biomaterials in vivo. In: Narayan, Roger J. ed. Monitoring and Evaluation of Biomaterials and their Performance In Vivo. Woodhead Publishing Series in Biomaterials. Elsevier, pp. 81–110.



In this chapter we have sought to provide readers with an overview of in vivo techniques currently used for the imaging of biomineralisation materials. To achieve this we have provided a background of what biomineralisation entails and why there is a need for biomaterials. Furthermore, we have briefly reviewed some of the in vitro techniques used for the basic understanding of mineralisation events and the prediction of how the materials may behave in vivo. For the latter we have attempted to guide the reader through how the techniques work and how they are used to monitor the biomineralisation process, with focus on integration of the implanted material with its surroundings. The technologies described here are constantly being updated, guided by the complexity in monitoring needs. We therefore advise the reader to update this list regularly.

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