Histone code, human growth and cancer.

Crea, Francesco (2012). Histone code, human growth and cancer. Oncotarget, 3(1) pp. 1–2.

DOI: https://doi.org/10.18632/oncotarget.435


Future studies should shed new light on the complex relationship between HPTMs and human development. In particular, the molecular function of EZH2 and NSD1 in bone development should be addressed. Moreover, histone methylation and demethylation may be modulated by novel small molecule inhibitors, which may pave the way to a therapeutic approach for those rare syndromes.

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