Engineering biofilms for biocatalysis

Tsoligkas, Andreas N.; Winn, Michael; Bowen, James; Overton, Tim W.; Simmons, Mark J. H. and Goss, Rebecca J. M. (2011). Engineering biofilms for biocatalysis. ChemBioChem, 12(9) pp. 1391–1395.



Biofilm, friend not foe: Single species biofilms can be engineered to form robust biocatalysts with greater catalytic activity and significantly improved catalytic longevity than purified and immobilised enzymes. We report the engineering, structural analysis and biocatalytic capability of a biofilm that can mediate the conversion of serine and haloindoles to halotryptophans.

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