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Medvedev, Nikolay; Popov, Victor; Henneberger, Christian; Kraev, Igor; Rusakov, Dmitri and Stewart, Michael
(2014).
DOI: https://doi.org/10.1098/rstb.2014.0047
Abstract
This paper examines the relationship between the morphological modality of 189 dendritic spines and the surrounding astroglia using full three dimensional reconstructions of neuropil fragments. An integrative measure of three-dimensional glial coverage confirms that thin spine PSDs are more tightly surrounded by glia. This distinction suggests that diffusion-dependent synapse–glia communication near ‘learning’ synapses (associated with thin spines) could be stronger than that near ‘memory’ synapses (associated with larger spines).