Aging of the mammalian gastrointestinal system

Saffrey, M. Jill (2011). Aging of the mammalian gastrointestinal system. In: 40th Annual American Aging Association meeting:'Mechanisms of Aging: Emerging Concepts', 4-6 Jun 2011, Raleigh, North Carolina, USA, pp. 44–45.


Gastrointestinal (GI) dysfunction is a common and distressing cause of morbidity in the aging population. Constipation and incontinence involve dysfunction of the large bowel, while efficient nutrient absorption and appetite may be affected by changes in the stomach and small intestine. Understanding the causes of physiological changes in the GI system requires analysis of cellular and molecular changes in the aging gut.

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