Investigating the effect of photodynamic therapy on nerves using tissue engineered culture models

Wright, K.E.; Liniker, E; MacRobert, A.J.; Brown, R.A.; Saffrey, M.J. and Phillips, J.B. (2006). Investigating the effect of photodynamic therapy on nerves using tissue engineered culture models. In: Tissue & Cell Engineering Society 2006, 3-4 Jul 2006, Sheffield, UK.

Abstract

Introduction: Photodynamic therapy (PDT) shows potential as an effective treatment for prostate cancer. Clinical observations indicate that this approach causes fewer nerve damage related side-effects than conventional treatments. The aim here is to investigate the effect of PDT on nerve tissue using engineered 3-dimensional cell culture models. Initial experiments focussed on establishing photosensitiser localisation in neurones and Schwann cells, then developing a model for simulating nerve PDT in culture.

Viewing alternatives

Item Actions

Export

You can export this page using these formats