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Barnard, Katharine D.; Lloyd, Cathy E. and Holt, Richard I. G.
(2012).
Abstract
Diabetes mellitus is a complex metabolic disorder characterized by persistent hyperglycemia (higher than normal blood glucose levels) resulting from defects in insulin secretion, insulin action, or both. It is one of the commonest long-term conditions and represents a major public health burden both in the UK and globally; it is estimated to affect approximately 3.1 million people in the UK alone and approximately 285 million people worldwide. By 2030, it is projected that this figure will rise to more than 435 million as a result of changing population demographics, such as aging and urbanization, changes in lifestyle, such as diet and exercise, and the associated increase in obesity.