Idiopathic thrombocytopenic purpura and MMR vaccine

Miller, E.; Waight, P; Farrington, C. P.; Andrews, N.; Stowe, J. and Taylor, B. (2001). Idiopathic thrombocytopenic purpura and MMR vaccine. Archives of Disease in Childhood, 84(3) pp. 227–229.

DOI: https://doi.org/10.1136/adc.84.3.227

Abstract

A causal association between measles mumps–rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.

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