Three-dimensional cell culture

MacQueen, Hilary; Loughlin, Jane and Daya, Sandeep (2007). Three-dimensional cell culture. The Open University, PCT/GB2007/050161.



The present invention relates to a three-dimensional cell culture system for culturing adipocytes. The invention also relates to methods for culturing adipocytes and for obtaining adipocytes from preadipocytes in cell culture. Aspects of the invention further relate to methods for evaluating interactions between adipocytes and other cell types, and for evaluating responses of adipocytes to environmental stimuli. This enables a greater understanding of the mechanisms involved in cell and tissue interactions and has implications in the fields of obesity, diabetes, inflammation and related diseases.

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