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Musonda, Patrick; Hocine, Mounia N.; Andrews, Nick J.; Tubert-Bitter, Pascale and Farrington, Paddy C.
(2008).
DOI: https://doi.org/10.1016/j.vaccine.2008.08.010
Abstract
We adapt the self-controlled case series method for routine surveillance of vaccine safety using cumulative sum (CUSUM) charts. The CUSUM surveillance method we propose is applicable for detecting associations that arise in a short pre-determined risk period following vaccination. The performance of the case series CUSUM is investigated through simulations. We illustrate the method using retrospective analyses of influenza vaccine and Bell's palsy, and MMR vaccine and febrile convulsions.
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About
- Item ORO ID
- 15751
- Item Type
- Journal Item
- ISSN
- 0264-410X
- Project Funding Details
-
Funded Project Name Project ID Funding Body Not Set Not Set MRC (Medical Research Council) Not Set Not Set EPSRC (Engineering and Physical Sciences Research Council) Not Set Not Set Fondation pour la Recherche Médicale - Keywords
- adverse event; self-controlled case series method; CUSUM; average run length; surveillance; vaccine
- Academic Unit or School
-
Faculty of Science, Technology, Engineering and Mathematics (STEM) > Mathematics and Statistics
Faculty of Science, Technology, Engineering and Mathematics (STEM) - Copyright Holders
- © 2008 Elsevier Ltd.
- Depositing User
- Colin Smith