New trends in aptamer-based electrochemical biosensors

Velasco-Garcia, Maria and Missailidis, Sotiris (2009). New trends in aptamer-based electrochemical biosensors. Gene Therapy and Molecular Biology, 13(1) pp. 1–10.

URL: http://web.ebscohost.com.libezproxy.open.ac.uk/eho...

Abstract

The analytical characteristics of aptamers are comparable with those of antibodies for the development of biosensor technology. However, aptamers offer some crucial advantages over antibodies such as selection capability for a variety of targets, easy synthesis, improved reproducibility and stability, simple modification for immobilization to solid supports and enhanced selectivity. This article reviews aptamer technology as well as aptamer-based assay configurations and goes on to explore reported applications in electrochemical aptasensors.

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