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Number of items: 35.


Miyata, Shoma; Hoshino, Mina; Isozaku, Tasuku; Yamada, Takeshi; Sugimura, Hideyuki; Xu, Yao-Zhong and Suzuki, Tadashi (2018). Acid Dissociation Equilibrium and Singlet Molecular Oxygen Quantum Yield of Acetylated 6,8–Dithioguanosine in Aqueous Buffer Solution. Journal of Physical Chemistry B, 122(11) pp. 2912–2921. restricted access item, not available for direct download

Miyata, Shoma; Yamada, Takeshi; Isozaki, Tasuku; Sugimura, Hideyuki; Xu, Yao-Zhong and Suzuki, Tadashi (2018). Absorption Characteristics and Quantum Yields of Singlet Oxygen Generation of Thioguanosine Derivatives. Photochemistry and Photobiology (Early view). restricted access item, not available for direct download


Moore, Elaine Ann and Xu, Yao-Zhong (2017). The effect of S-substitution at the O6-guanine site on the structure and dynamics of a DNA oligomer containing a G:T mismatch. PLoS ONE, 12(9), article no. e0184801. file


Zhang, Xiao-Hui and Xu, Yao-Zhong (2016). NMR studies on 4-thio-5-furan-modified and 4-thio-5-thiophene-modified nucleosides. Magnetic Resonance in Chemistry, 54(11) pp. 887–892. file

Zhang, Xiaohui; Yan, Defeng; Ma, Kedong; He, Lingshuang; Gao, Ruiqi; Xu, Yaozhong and Li, Depeng (2016). The Synthesis of (E)-4-Thio-5-(2-Bromovinyl)Uridine/Deoxyuridine and Its Characterization and Cytotoxicity. Chinese Journal of Organic Chemistry, 36(12) pp. 2989–2996. file

Ge, Jiang; Feng, Luo; Yaozhong, Xu and Xiaohui, Zhang (2016). UVA Assisted 4-Thiothymidine for Cancer Treatment. Progress in Chemistry, 28(8) pp. 1224–1237. file

Zhang, Xiaohui; Li, Depeng; Qin, Jianzhong; Xu, Yaozhong and Ma, Kedong (2016). Synthesis of 4-thio-5-(2′′-thienyl)uridine and cytotoxicity activity against colon cancer cells in vitro. RSC Advances, 6(74) pp. 70099–70105. file


Brem, Reto; Zhang, Xiaohui; Xu, Yao-Zhong and Karran, Peter (2015). UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions. Journal of Photochemistry and Photobiology B: Biology, 145(4) pp. 1–10. file

Narukulla, Raman and Xu, Yao-Zhong (2015). Nucleotides and oligonucleotides: mononucleotides. In: Allen, David; Tebby, John C. and Loakes, David eds. Organophosphorus Chemistry, Volume 44. Cambridge: The Royal Society of Chemistry, pp. 170–192. restricted access item, not available for direct download

Trigiante, Guiseppe and Xu, Yao-Zhong (2015). 4-thiothymidine and its analogues as UVA-activated photosensitizers. In: Hugo, Adrian G. ed. Photodynamic Therapy: Fundamentals, Applications and Health Outcomes. Cancer Etiology, Diagnosis and Treatments. Hauppauge, NY: Nova SciencePublishers, pp. 193–206.

Zhang, Xiao-Hui; Yin, Hong-Yan; Trigiante, Joseph; Brem, Reto; Karran, Peter; Pitak, Mateusz B.; Coles, Simon J. and Xu, Yao-Zhong (2015). 5-iodo-4-thio-2′-deoxyuridine: synthesis, structure, and cytotoxic activity. Chemistry Letters, 44(2) pp. 147–149. file


Xu, Yao-Zhong and Narukulla, Raman (2014). Nucleotides and oligonucleotides: mononucleotides. In: Allen, David; Tebby, John C. and Loakes, David eds. Organophosphorus Chemistry, Volume 43. Cambridge: The Royal Society of Chemistry, pp. 117–145.

Pitman, Simone; Xu, Yao; Taylor, Peter and Turner, Nicholas (2014). Spotlight on medicinal chemistry education. Future Medicinal Chemistry, 6(8) pp. 865–869. file


Zhang, Xiaohui; Wang, Jian and Xu, Yao-Zhong (2013). Systematic assignment of NMR spectra of 5-substituted-4-thiopyrimidine nucleosides. Magnetic Resonance in Chemistry, 51(9) pp. 523–529. restricted access item, not available for direct download

Gemenetzidis, Emilios; Shavorskaya, Oksana; Xu, Yao-Zhong and Trigiante, Giuseppe (2013). Topical 4-thiothymidine is a viable photosensitiser for the photodynamic therapy of skin malignancies. Journal of Dermatological Treatment, 24(3) pp. 209–214.


Yin, Hong-yan; Zhang, Xiao-hui and Xu, Yao-zhong (2011). Study on synthesis and fluorescence spectra of 5-bromor-4-thio-2′-deoxyuridine labeled with monobromobimanes fluorescein. Journal of Molecular Science, 27(6) pp. 397–401. file

Zhang, Xiaohui and Xu, Yao-Zhong (2011). NMR and UV studies of 4-Thio-2′-deoxyuridine and its derivatives. Molecules, 16(7) pp. 5655–5664. file

Pridgeon, S. W.; Heer, R.; Taylor, G. A.; Newell, D. R.; O'Toole, K.; Robinson, M.; Xu, Y-Z; Karran, P. and Boddy, A. V. (2011). Thiothymidine combined with UVA as a potential novel therapy for bladder cancer. British Journal of Cancer, 104(12) pp. 1869–1876. restricted access item, not available for direct download

Reelfs, Olivier; Macpherson, Peter; Ren, Xiaolin; Xu, Yao-Zhong; Karran, Peter and Young, Antony R. (2011). Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells. Nucleic Acids Research, 39(22) pp. 9620–9632. file


Ren, Xiaolin; Xu, Yao-Zhong and Karren, Peter (2010). Photo-oxidation of 6-thioguanine by UVA: the formation of addition products with low molecular weight thiol compounds. Photochemistry and Photobiology, 86(5) pp. 1038–1045.

Zhang, X. H.; Wang, A. L.; Li, D. P. and Xu, Y.-Z. (2010). UVA light-assisted anticancer drugs - study on 4-thiothymidine and its analogues. Progress in Chemistry, 22(5) pp. 784–795. file

Ren, Xiaolin; Li, Feng; Jeffs, Graham; Zhang, Xiaohong; Xu, Yao-Zhong and Karran, Peter (2010). Guanine sulphinate is a major stable product of photochemical oxidation of DNA 6-thioguanine by UVA irradiation. Nucleic Acids Research, 38(6) pp. 1832–1840. file

Harada, Yosuke; Okabe, Chie; Kobayashi, Takashi; Suzuki, Tadashi; Ichimura, Teijiro; Nishi, Nobuyuki and Xu, Yao-Zhong (2010). Ultrafast intersystem crossing of 4-Thiothymidine inaqueous solution. Journal of Physical Chemistry Letters, 1(2) pp. 480–484. restricted access item, not available for direct download


Narukulla, Raman; Shuker, David E. G.; Ramesh, Vasudevan and Xu, Yao-Zhong (2008). Unambiguous structural elucidation of base-modified purine nucleosides using NMR. Magnetic Resonance in Chemistry, 46(1) pp. 1–8.


Montaneri, Beatriz; O'Donovan, Peter; Reelfs, Olivier; Perrett, Conal M; Zhang, Xiaohong; Xu, Yao-Zhong; Ren, Xiaolin; Macpherson, Peter; Frith, David and Karran, Peter (2007). Reactive oxygen-mediated damage to a human DNA replication and repair protein. EMBO Reports, 8(11) pp. 1074–1079.

Reelfs, Olivier; Xu, Yao-Zhong; Massey, Andrew; Karran, Peter and Storey, Alan (2007). Thiothymidine plus low-dose UVA kills hyperproliferativehuman skin cells independently of their human papilloma virus status. Molecular Cancer Therapeutics, 6 pp. 2487–2495. file

Harada, Y; Suzuki, T; Ichimura, T and Xu, YZ (2007). Triplet Formation of 4-Thiothymidine and Its Photosensitization to Oxygen Studied by Time-Resolved Thermal Lensing Technique. Journal of Physical Chemistry B, 111(19) pp. 5518–5524.

Zhang, Xiaohong; Jeffs, Graham; Ren, Xiaolin; O'Donovan, Peter; Montaner, Beatriz; Perrett, Conal M.; Karran, Peter and Xu, Yao-Zhong (2007). Novel DNA lesions generated by the interaction between therapeutic thiopurines and UVA light. DNA Repair, 6(3) pp. 344–354.


O'Donovan, Peter; Perrett, Conal M.; Zhang, Xiaohong; Montaner, Beatriz; Xu, Yao-Zhong; Harwood, Catherine A.; McGregor, Jane M.; Walker, Susan L.; Hanaoka, Fumio and Karran, Peter (2005). Azathioprine and UVA Light generate mutagenic oxidative DNA damage. Science, 309(5742) pp. 1871–1874.

Narukulla, Raman; Shuker, David E.G. and Xu, Yao-Zhong (2005). Post-synthetic and site-specific modification of endocyclic nitrogen atoms of purines in DNA and its potential for biological and structural studies. Nucleic Acids Research, 33(6) pp. 1767–1778. file

Lari, Sibghat-Ullah; Xu, Yao-Zhong and Day, Rufus S. (2005). Evidence for three thymine DNA glycosylases in human cell extracts: substrate specific cities of thymine DNA glycosylase activities. Medical Science Monitor, 11(2) pp. 41–49.


Xu, Yao-Zhong; Zhang, Xiaohui; Wu, Hai-Chen; Massey, Andrew and Karran, Peter (2004). 4-Thio-5-bromo-2′-deoxyuridine: chemical synthesis and therapeutic potential of UVA-induced DNA damage. Bioorganic and Medicinal Chemistry Letters, 14(4) pp. 995–997.


Massey, Andrew; Xu, Yao-Zhong and Karran, Peter (2002). Ambiguous coding is required for the lethal interaction between methylated DNA bases and DNA mismatch repair. DNA Repair, 1(4) pp. 275–286.

Xu, Yao-Zhong (2002). Synthetic chemistry of base-modified DNA and their biological applications. In: Loakes, David ed. Modified Nulceoside, Synthesis and Applications. Kerala, India: Research Signpost, pp. 1–16.


Massey, Andrew; Xu, Yao-Zhong and Karran, Peter (2001). Photoactivation of DNA thiobases as a potential novel therapeutic option. Current Biology, 11(14) pp. 1142–1146.

This list was generated on Sun May 20 16:34:33 2018 BST.

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