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Number of items: 84.


Raghnaill, Michelle Nic; Bramini, Mattia; Ye, Dong; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Aberg, Christoffer; Salvati, Anna; Lynch, Iseult and Dawson, Kenneth A. (2014). Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles. The Analyst, 139(5) pp. 923–930.

Qosa, Hisham; Abuasal, Bilal S.; Romero, Ignacio A.; Weksler, Babette; Couraud, Pierre-Oliver; Keller, Jeffrey N. and Kaddoumi, Amal (2014). Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling. Neuropharmacology, 79 pp. 668–678.

Noack, Andreas; Noack, Sandra; Hoffmann, Andrea; Maalouf, Katia; Buettner, Manuela; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Alms, Dana; Römermann, Kerstin; Naim, Hassan Y. and Löscher, Wolfgang (2014). Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C. PloS one, 9(2) article e88154.


Gromnicova, Radka; Davies, Heather A.; Sreekanthreddy, Pedagannganagari; Romero, Ignacio A.; Lund, Torben; Roitt, Ivan M.; Phillips, James B. and Male, David K. (2013). Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro. PLoS ONE, 8(12) article e81043. file

Lopez-Ramirez, Miguel Alejandro; Male, David Kingsley; Wang, Chunfang; Sharrack, Basil; Wu, Dongsheng and Romero, Ignacio Andres (2013). Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3. Fluids and Barriers of the CNS, 10(1) article 27.

Chaitanya, Ganta V.; Cromer, Walter E.; Parker, Courtney P.; Couraud, Pierre O.; Romero, Ignacio A; Weksler, Babette; Mathis, J. Michael; Minagar, Alireza and Alexander, J. Steven (2013). A recombinant inhibitory isoform of vascular endothelial growth factor164/165 aggravates ischemic brain damage in a mouse model of focal cerebral ischemia. American Journal of Pathology, 183(3) pp. 1010–1024.

Basivireddy, Jayasree; Somvanshi, Rishi K.; Romero, Ignacio A; Weksler, Babette B.; Couraud, Pierre-Olivier; Oger, Joel and Kumar, Ujendra (2013). Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis. Biochemical pharmacology, 86(4) pp. 497–507.

Reuter, B.; Rodemer, C.; Grudzenski, S.; Couraud, P.-O.; Weksler, B.; Romero, Ignacio A; Meairs, S.; Bugert, P.; Hennerici, M. G and Fatar, M. (2013). Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia. Cerebrovascular Diseases, 35(6) pp. 514–520.

Dickens, David; Yusof, Siti R.; Abbott, N. Joan; Weksler, Babette; Romero, Ignacio A; Couraud, Pierre-Olivier; Alfirevic, Ana; Pirmohamed, Munir and Owen, Andrew (2013). A multi-system approach assessing the interaction of anticonvulsants with P-gp. PLoS ONE, 8(5) article e64854.

Duan, Hongxia; Xing, Shu; Luo, Yongting; Feng, Liqun; Gramaglia, Irene; Zhang, Ying; Lu, Di; Zeng, Qiqun; Fan, Kelong; Feng, Jing; Yang, Dongling; Qin, Zhihai; Couraud, Pierre-Olivier; Romero, Ignacio A; Weksler, Babette and Yan, Xiyun (2013). Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS. Scientific reports, 3 article 1687.

Reijerkerk, Arie; Lopez-Ramirez, M. Alejandro; van Het Hof, Bert; Drexhage, Joost A. R.; Kamphuis, Wouter W.; Kooij, Gijs; Vos, Joost B.; van der Pouw Kraan, Tineke C. T. M.; van Zonneveld, Anton J.; Horrevoets, Anton J.; Prat, Alexandre; Romero, Ignacio A and de Vries, Helga E. (2013). MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis. The Journal of Neuroscience , 33(16) pp. 6857–6863.

Bao Dang, Quoc; Lapergue, Bertrand; Tran-Dinh, Alexy; Diallo, Devy; Moreno, Juan-Antonio; Mazighi, Mikael; Romero, Ignacio A.; Weksler, Babette; Michel, Jean-Baptiste; Amarenco, Pierre and Meilhac, Olivier (2013). High-density lipoproteins limit neutrophil-induced damage to the blood–brain barrier in vitro. Journal of Cerebral Blood Flow & Metabolism, 33(4) pp. 575–582.

Griep, L. M.; Wolbers, F.; de Wagenaar, B.; ter Braak, P. M.; Weksler, B. B.; Romero, Ignacio A; Couraud, P. O.; Vermes, I.; van der Meer, A. D. and van den Berg, A. (2013). BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function. Biomedical Microdevices, 15(1) pp. 145–150.

Cristante, Enrico; McArthur, Simon; Mauro, Claudio; Maggioli, Elisa; Romero, Ignacio A.; Wylezinska-Arridge, Marzena; Couraud, Pierre O.; Lopez-Tremoleda, Jordi; Christian, Helen C.; Weksler, Babette B.; Malaspina, Andrea and Solito, Egle (2013). Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proceedings of the National Academy of Sciences of the United States of America, 110(3) pp. 832–841.

Daniels, Brian P.; Cruz-Orengo, Lillian; Pasieka, Tracy Jo; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Cooper, John A.; Doering, Tamara L. and Klein, Robyn S. (2013). Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier. Journal of Neuroscience Methods, 212(1) pp. 173–179.

Navarro-Sobrino, Míriam; Hernández-Guillamon, Mar; Fernandez-Cadenas, Israel; Ribó, Marc; Romero, Ignacio A; Couraud, Pierre-Olivier; Weksler, Babette Barbash; Montaner, Joan and Rosell, Anna (2013). The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients. Vascular Cell, 5(3) p. 3.

Weksler, Babette; Romero, Ignacio A. and Couraud, Pierre-Olivier (2013). The hCMEC/D3 cell line as a model of the human blood brain barrier. Fluids and barriers of the CNS, 10(1) article 16.

Wang, C.; Saffrey, M. J. and Romero, I. A. (2013). Age-related changes in blood-brain barrier integrity in C57BL/6J mice. In: British Society for Research on Ageing Annual Scientific Meeting, 2-4 September 2013, Institute of Food Research, University of East Anglia, Norwich, p. 36. file


Pinzón-Daza, M. L.; Garzón, R.; Couraud, P. O.; Romero, I. A.; Weksler, B.; Ghigo, D.; Bosia, A. and Riganti, C. (2012). The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases the in vitro drug delivery across blood-brain barrier cells. British Journal of Pharmacology, 167(7) pp. 1431–1447.

Li, Tengfei; Bourgeois, Jean-Pierre; Celli, Susanna; Glacial, Fabienne; Le Sourd, Anne-Marie; Mecheri, Salah; Weksler, Babette; Romero, Ignacio; Couraud, Pierre-Olivier; Rougeon, François and Lafaye, Pierre (2012). Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging. FASEB Journal, 26(10) pp. 3969–3979.

Gromnicova, Radka; Romero, Ignacio A and Male, David (2012). Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues. PLoS ONE, 7(10) article e48189. file

Laakkonen, Johanna P.; Engler, Tatjana; Romero, Ignacio A; Weksler, Babette; Couraud, Pierre-Olivier; Kreppel, Florian and Kochanek, Stefan (2012). Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro. PLoS ONE, 7(9) e45977.

Roberts, Toni K; Eugenin, Eliseo A; Lopez, Lillie; Romero, Ignacio A; Weksler, Babette B; Couraud, Pierre-Olivier and Berman, Joan W (2012). CCL2 disrupts the adherens junction: implications for neuroinflammation. Laboratory investigation; a journal of technical methods and pathology, 92(8) pp. 1213–1233.

Kooijmans, Sander A. A.; Senyschyn, Danielle; Mezhiselvam, Muguntha M.; Morizzi, Julia; Charman, Susan A.; Weksler, Babette; Romero, Ignacio-Andres; Couraud, Pierre-Olivier and Nicolazzo, Joseph A. (2012). The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine. Molecular pharmaceutics, 9(4) pp. 883–93.

Dickens, David; Owen, Andrew; Alfirevic, Ana; Giannoudis, Athina; Davies, Andrea; Weksler, Babette; Romero, Ignacio A; Couraud, Pierre-Olivier and Pirmohamed, Munir (2012). Lamotrigine is a substrate for OCT1 in brain endothelial cells. Biochemical pharmacology, 83(6) pp. 805–14.

Fletcher, Nicola F.; Wilson, Garrick K.; Murray, Jacinta; Hu, Ke; Lewis, Andrew; Reynolds, Gary M.; Stamataki, Zania; Meredith, Luke W.; Rowe, Ian A.; Luo, Guangxiang; Lopez-Ramirez, Miguel A.; Baumert, Thomas F.; Weksler, Babette; Couraud, Pierre-Olivier; Kim, Kwang Sik; Romero, Ignacio A.; Jopling, Catherine; Morgello, Susan; Balfe, Peter and McKeating, Jane A. (2012). Hepatitis C Virus infects the endothelial cells of the blood-brain barrier. Gastroenterology, 142(3) 634-643.e6.

Fouillet, A.; Mawson, J.; Suliman, O.; Sharrack, B.; Romero, I. A. and Woodroofe, M. N. (2012). CCL2 binding is CCR2 independent in primary adult human astrocytes. Brain research, 1437 pp. 115–26.

Watson, Christopher P.; Dogruel, Murat; Mihoreanu, Larisa; Begley, David J.; Weksler, Babette B.; Couraud, Pierre O.; Romero, Ignacio A. and Thomas, Sarah A. (2012). The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: Evidence for involvement of breast cancer resistance protein. Brain research, 1436 pp. 111–121.

Bintig , Willem; Begandt , Daniela; Schlingmann , Barbara; Gerhard , Linda; Pangalos , Maria; Dreyer , Lutz; Hohnjec , Natalija; Couraud , Pierre-Olivier; Romero, Ignacio A; Weksler, Babette B. and Ngezahayo , Anaclet (2012). Purine receptors and Ca2+ signalling in the human blood-brain barrier endothelial cell line hCMEC/D3. Purinergic Signalling, 8(1) pp. 71–80.

Schrade, Anja; Sade, Hadassah; Couraud, Pierre-Olivier; Romero, Ignacio A; Weksler, Babette B and Niewoehner, Jens (2012). Expression and localization of claudins-3 and -12 in transformed human brain endothelium. Fluids and barriers of the CNS, 9 p. 6.

Freese, Christian; Uboldi, Chiara; Gibson, Matthew I.; Unger, Ronald E.; Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre-Olivier and Kirkpatrick, C. J. (2012). Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells. Particle and Fibre Toxicology, 9 article 23. file

Lopez-Ramirez, Alejandro; Fischer, Roman; Torres-Badillo, Claudia C.; Davies, Heather A.; Logan, Karen; Pfizenmaier, Klaus; Male, David K.; Sharrack, Basil and Romero, Ignacio A. (2012). Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells. Journal of Immunology, 189(6) pp. 3130–3139.


Hatherell, Kathryn; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette and Pilkington, Geoffrey J. (2011). Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models. Journal of neuroscience methods, 199(2) pp. 223–229.

Shen, Weiyong; Li, Shiying; Chung, Sook Hyun; Zhu, Ling; Stayt, Jason; Su, Tao; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette and Gillies, Mark C. (2011). Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. European Journal of Cell Biology, 90(4) pp. 323–332. file

Markoutsa, Eleni; Pampalakis, Georgios; Niarakis, Anna; Romero, Ignacio A.; Weksler, Babette; Couraud, Pierre-Olivier and Antimisiaris, Sophia G. (2011). Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line. European Journal of Pharmaceutics and Biopharmaceutics, 77(2) pp. 265–274. file

Georgieva, Julia V.; Kalicharan, Dharamdajal; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Hoekstra, Dick and Zuhorn, Inge S (2011). Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood–brain barrier endothelial cells in vitro. Molecular Therapy (In Press).

Mills, Jeffrey H.; Alabanza, Leah; Weksler, Babette B.; Couraud, Pierre-Olivier; Romero, Ignacio A. and Bynoe, Margaret S. (2011). Human brain endothelial cells are responsive to adenosine receptor activation. Purinergic Signalling, 7(2) pp. 265–273.

Chaitanya, Ganta V.; Cromer, Walter E.; Wells, Shannon R.; Jennings, Merilyn H.; Couraud, P. Oliver; Romero, Ignacio A; Weksler, Babette; Erdreich-Epstein, Anat; Mathis, James Michael; Minagar, Alireza and Alexander, J. Steven (2011). Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro. Journal of Neuroinflammation, 8(162)

Faria, Ana; Pestana, Diogo; Teixeira, Diana; Couraud, Pierre-Olivier; Romero, Ignacio A; Weksler, Babette; de Freitas, Victor; Mateus, Nuno and Calhau, Conceição (2011). Insights into the putative catechin and epicatechin transport across blood-brain barrier. Food & Function(2) pp. 39–44.


Bhattacharya, Raktima; Xu, Yan; Rahman, Md. Ashequr; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette B.; Weidanz, Jon A. and Bickel, Ulrich (2010). A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody. Journal of Cellular Physiology, 225(3) pp. 664–672. file

Carl, Stephen M.; Lindley, David J.; Couraud, Pierre O.; Weksler, Babette B.; Romero, Ignacio; Mowery, Stephanie A. and Knipp, Gregory T. (2010). ABC and SLC transporter expression and POT substrate characterization across the human CMEC/D3 blood-brain barrier cell line. Molecular Pharmaceutics, 7(4) pp. 1057–1068. file

Tai, L. M.; Holloway, K. A.; Male, D. K.; Loughlin, A. J. and Romero, I. A (2010). Amyloid-β-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation. Journal of Cellular and Molecular Medicine, 14(5) pp. 1101–1112. file

Fossati, S.; Cam, J.; Meyerson, J.; Mezhericher, E.; Romero, I. A.; Couraud, P. O.; Weksler, B. B.; Ghiso, J. and Rostagno, A. (2010). Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-β variants in cells composing the cerebral vessel walls. FASEB Journal, 24(1) pp. 229–241.

Najbauer, Joseph; Haarmann, Axel; Deiß, Annika; Prochaska, Jürgen; Foerch, Christian; Weksler, Babette; Romero, Ignacio; Couraud, Pierre-Olivier; Stoll, Guido; Rieckmann, Peter and Buttmann, Mathias (2010). Evaluation of soluble junctional adhesion molecule-a as a biomarker of human brain endothelial barrier breakdown. PLoS ONE, 5(10) e13568. file

van Rooy, Inge; Cakir-Tascioglu, Serpil; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Storm, Gert; Hennink, Wim E.; Schiffelers, Raymond M. and Mastrobattista, Enrico (2010). Identification of peptide ligands for targeting to the blood-brain barrier. Pharmaceutical Research, 27(4) pp. 673–682. file


Ramirez, Servio H.; Potula, Raghava; Fan, Shongshan; Eidem, Tess; Papugani, Anil; Reichenbach, Nancy; Dykstra, Holly; Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre O. and Persidsky, Yuri (2009). Methamphetamine disrupts blood–brain barrier function by induction of oxidative stress in brain endothelial cells. Journal of Cerebral Blood Flow and Metabolism, 29(12) pp. 1933–1945.

Vu, Kiem; Weksler, Babette; Romero, Ignacio A; Couraud, Pierre-Olivier and Gelli, Angie (2009). Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection by Cryptococcus neoformans. Eukaryotic Cell, 8(11) pp. 1803–1807.

Joice, Shannon L.; Mydeen, Firdau; Couraud, Pierre-Olivier; Weksler, Babette B.; Romero, Ignacio A.; Fraser, Paul A. and Easton, Alexander S. (2009). Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies. Brain Research, 1298 pp. 13–23. file

Tai, Leon M.; Reddy, P. Sreekanth; Lopez-Ramirez, M. Alejandro; Davies, Heather A.; Male, A. David K.; Loughlin, A. Jane and Romero, Ignacio A. (2009). Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123. Brain Research, 1292 pp. 14–24. file

Fischer, Silvia; Nishio, Miwako; Peters, Saskia C.; Tschernatsch, Marlene; Walberer, Maureen; Weidemann, Susanne; Heidenreich, Regina; Couraud, Pierre O.; Weksler, Babette B.; Romero, Ignacio A.; Gerriets, Tibo and Preissner, Klaus T. (2009). Signaling mechanism of extracellular RNA in endothelial cells. FASEB Journal, 23(7) pp. 2100–2109.

Coureuil, Mathieu; Mikaty, Guillain; Miller, Florence; Lécuyer, Hervé; Bernard, Christine; Bourdoulous, Sandrine; Duménil, Guillaume; Mège, René-Marc; Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre Olivier and Nassif, Xavier (2009). Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. Science, 325(5936) pp. 83–87.

Tai, Leon M.; Loughlin, A. Jane; Male, David K. and Romero, Ignacio A. (2009). P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-β. Journal of Cerebral Blood Flow and Metabolism, 29(6) pp. 1079–1083.

Hurst, Louise A.; Bunning, Rowena A.D.; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette B.; Sharrack, Basil and Woodroofe, M. Nicola (2009). Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment. Journal of Neuroimmunology, 210(1-2) pp. 108–112.

Vukic, Vanja; Callaghan, Debbie; Walker, David; Lue, Lih-Fen; Liu, Qing Yan; Couraud, Pierre-Oliver; Romero, Ignacio A.; Weksler, Babette; Stanimirovic, Danica B. and Zhang, Wandong (2009). Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiology of Disease, 34(1) pp. 95–106.

Zastre, Jason A.; Chan, Gary N. Y.; Ronaldson, Patrick T.; Ramaswamy, Manisha; Couraud, Pierre O.; Romero, Ignacio A.; Weksler, Babette; Bendayan, Moise and Bendayan, Reina (2009). Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line. Journal of Neuroscience Research, 87(4) pp. 1023–1036.

Dauchy, Sandrine; Miller, Florence; Couraud, Pierre-Olivier; Weaver, Richard, J.; Weksler, Babette; Romero, Ignacio A.; Scherrmann, Jean-Michel; De Waziers, Isabelle and Decleves, Xavier (2009). Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells. Biochemical Pharmacology, 77(5) pp. 897–909.

Sade, Hadassah; Holloway, Karen; Romero, Ignacio A. and Male, David (2009). Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1789(3) pp. 175–184. file

Subileau, Eve A; Rezaie, Payam; Davies, Heather; Colyer, Frances; Greenwood, John; Male, David and Romero, Ignacio A (2009). Expression of chemokines and their receptors by human brain endothelium: Implications for multiple sclerosis. Journal of Neuropathology and Experimental Neurology, 68(3) pp. 227–240. file

Bahbouhi, Bouchaib; Berthelot, Laureline; Pettré, Ségolène; Michel, Laure; Wiertlewski, Sandrine; Weksler, Babette; Romero, Ignacio A.; Miller, Florence; Couraud, Pierre-Olivier; Brouard, Sophie; Laplaud, David-Axel and Soulillou, Jean-Paul (2009). Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line. Journal of Leukocyte Biology, 86(5) pp. 1049–1063.

Mkrtchyan, H.; Scheler, S.; Klein, I.; Fahr, A.; Couraud, P. O.; Romero, I. A.; Weksler, B. and Liehr, T. (2009). Molecular cytogenetic characterization of the human cerebral microvessel endothelial cell line hCMEC/D3. Cytogenetic and Genome Research, 126 pp. 313–317. file


Poller, Birk; Gutmann, Heike; Krahenbuhl, Stephan; Weksler, Babette; Romero, Ignacio A.; Couraud, Pierre-Olivier; Tuffin, Gerald; Drewe, Jürgen and Huwyler, Jörg (2008). The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies. Journal of Neurochemistry, 107(5) pp. 1358–1368.

Afonso, Philippe V.; Ozden, Simona; Cumont, Marie-Christine; Seilhean, Danielle; Cartier, Luis; Rezaie, Payam; Mason, Sarah; Lambert, Sophie; Huerre, Michel; Gessain, Antoine; Couraud, Pierre-Olivier; Pique, Claudine; Ceccaldi, Pierre-Emmanuel and Romero, Ignacio A. (2008). Alteration of blood–brain barrier integrity by retroviral infection. PLoS Pathogens, 4(11) article e1000205. file

Maru, Seema V.; Holloway, Karen A.; Flynn, Geraldine; Lancashire, Christine L.; Loughlin, A. Jane; Male, David K. and Romero, Ignacio A. (2008). Chemokine production and chemokine receptor expression by human glioma cells: Role of CXCL10 in tumour cell proliferation. Journal of Neuroimmunology, 199(1-2) pp. 35–45.

Wilhelm, Imola; Nagyoszi, Péter; Farkas, Attila E.; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Fazakas, Csilla; Dung, Ngo Thi Khue; Bottka, Sándor; Bauer, Hannelore; Bauer, Hans-Christian and Krizbai, István A. (2008). Hyperosmotic stress induces axl activation and cleavage in cerebral endothelial cells. Journal of Neurochemistry, 107(1) pp. 116–126. file

András, I. E.; Rha, G.; Huang, W.; Eum, S.; Couraud, P. O.; Romero, I. A.; Henning, B. and Toborek, M. (2008). Simvastatin Protects against Amyloid β and HIV-1 Tat-Induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells. Molecular Pharmacology, 73(5) pp. 1424–1433.

Förster, C.; Burek, M.; Romero, I. A.; Weksler, B.; Couraud, P. O. and Drenckhahn, D. (2008). Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. Journal of Physiology, 586(7) pp. 1937–1949. file

Cucullo, Luca; Couraud, Pierre-Olivier; Weksler, Babette; Romero, Ignacio-Andres; Hossain, Mohammed M; Rapp, Edward and Janigro, Damir (2008). Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies. Journal of Cerebral Blood Flow and Metabolism, 28(2) pp. 312–328.

Lim, Joseph C.; Kania, Katarzyna D.; Wijesuriya, Hasini; Chawla, Sangeeta; Sethi, Jaswinder K.; Pulaski, Lukasz; Romero, Ignacio A.; Couraud, Pierre O.; Weksler, Babette B.; Hladky, Stephen B. and Barrand, Margery A. (2008). Activation of β-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells. Journal of Neurochemistry, 106(4) pp. 1855–1865.


Schreibelt, G.; Kooij, G.; Reijerkerk, A.; van Doorn, R.; Gringhuis, S.I.; van der Poll, S.M.A.; Weksler, B.B.; Romero, Ignacio A; Couraud, P.O.; Piontek, J.; Blasig, I.E.; Dijkstra, Christine D.; Ronken, E. and de Vries, H.E. (2007). Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB Journal, 21(13) pp. 3666–3676.

Wilhelm, Imola; Farkas, Attila E.; Nagyoszi, Peter; Varo, Gyorgy; Balint, Zoltan; Vegh, Gergely A.; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette and Krizbai, Istvan A. (2007). Regulation of cerebral endothelial cell morphology by extracellular calcium. Physics in medicine and biology, 52(20) pp. 6261–6274.

Afonso, P.V.; Ozden, S.; Prevost, M.C.; Schmitt, C.; Seilhan, D.; Weksler, B.B.; Couraud, P.O.; Gessain, A.; Romero, I.A. and Ceccaldi, P.E. (2007). Human Blood Brain Barrier Disruption by Retroviral Infected Lymphocytes: Role of Myosin Light Chain Kinase in Endothelial Tight-Junction Disorganization. Journal of Immunology, 179(4) pp. 2576–2583.

Holloway, Karen; Sade, Hadassah; Romero, Ignacio A. and Male, David (2007). Action of transcription factors in the control of transferrin receptor expression in human brain endothelium. Journal of Molecular Biology, 365(5) pp. 1271–1284. file


Couraud, P.O.; Romero, I.A. and Weksler, B.B. (2006). Human Blood Brain Barrier Model. INSERM; Cornell University; Couraud, P.O.; Romero, I.A.; Weksler, B.B., WO/2006/056879.


Weksler, B.B.; Subileau, E.A.; Perriere, N.; Charneau, P.; Holloway, K.; Leveque, M.; Tricoire-Leignel, H.; Nicotra, A.; Bourdolos, S.; Tourowski, P.; Male, D.K.; Roux, F.; Greenwood, J.; Romero, I.A. and Couraud, P.O. (2005). Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB Journal, 19(13) pp. 1872–1874.


Bailey, T. A.; Kanuga, N.; Romero, I. A.; Greenwood, J.; Luthert, P. J. and Cheetham, M. E. (2004). Oxidative stress affects the junctional integrity of retinal pigment epithelial cells. Investigative Ophthalmology and Visual Science, 45(2) pp. 675–684.


Didier, Nathalie; Romero, Ignacio A.; Creminon, Christophe; Wijkhuisen, Anne; Grassi, Jacques and Mabondzo, Aloise (2003). Secretion of interleukin-1β by astrocytes mediates endothelin-1 and tumour necrosis factor-α effects on human brain microvascular endothelial cell permeability. Journal of Neurochemistry, 86(1) pp. 246–254.

Romero, I.A.; Radewicz, K.; Jubin, E.; Michel, C.C.; Greenwood, J.; Couraud, P.O. and Adamson, P. (2003). Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells. Neuroscience Letters, 344(2) pp. 112–116.

Flynn, Geraldine; Maru, Seema; Loughlin, Jane; Romero, Ignacio A. and Male, David (2003). Regulation of chemokine receptor expression in human microglia and astrocytes. Journal of Neuroimmunology, 136(1-2) pp. 84–93.

Xeniou, Ourania; Romero, Ignacio A and Saffrey, Jill (2003). Effects of neurotrophic factors on neurochemical differentiation of postnatal rat myenteric plexus ganglion cells in vitro. In: British Neuroscience Association 17th National meeting, 13-16 April, 2003, Harrogate, UK, British Neuroscience Association, p. 48.

Xeniou, O.; Romero, I. and Saffrey, M. J. (2003). The role of neurotrophic factors and extracellular matrix components in postnatal myenteric neuronal differentiation. In: Enteric Nervous System 2003, An International Conference devoted to studies of the enteric nervous system, 9-13 July, 2003, Banff, Alberta, Canada, Blackwell, p. 201.


Romero, I.A.; Amos, C.L.; Greenwood, J. and Adamson, P. (2002). Ezrin and moesin co-localise with ICAM-1 in brain endothelial cells but are not directly associated. Molecular Brain Research, 105(1-2) pp. 47–59.

Romero, Ignacio A.; Hazan, Uriel; Cancello, Raffaella; Valente, Susana; Perrin, Virginie; Mariot, Virginie; Dumonceaux, Julie; Cindy C., Gerhardt; Strosberg, A. Donny; Courard, Pierre-Olivier and Pietri-Rouxel, France (2002). Human adipose cells express CD4, CXCR4, and CCR5 receptors: a new target cell type for the immunodeficiency virus-1? FASEB Journal, 16(8) pp. 1254–1256.


Gerhardt, C. C.; Romero, Ignacio A; Cancello, R.; Camoin, L. and Strosberg, A. D. (2001). Chemokines control fat accumulation and leptin secretion by cultured human adipocytes. Molecular and cellular endocrinology, 175(1 - 2) pp. 81–92.

Amos, Claire; Romero, Ignacio A.; Schulze, Charlotte; Rousell, Jonathan; Pearson, Jeremy D.; Greenwood, John and Adamson, Peter (2001). Cross-linking of brain endothelial intercellular adhesion molecule (ICAM)-1 induces association of ICAM-1 with detergent-insoluble cytoskeletal fraction. Arteriosclerosis, Thrombosis, and Vascular Biology, 21 pp. 810–816.

This list was generated on Wed Apr 16 22:49:05 2014 BST.

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