Items Authored or Edited by Ignacio A Romero
Number of items: 70. 2013
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Griep, L. M.; Wolbers, F.; de Wagenaar, B.; ter Braak, P. M.; Weksler, B. B.; Romero, Ignacio A; Couraud, P. O.; Vermes, I.; van der Meer, A. D. and van den Berg, A.
(2013).
BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function.
Biomedical Microdevices, 15(1)
pp. 145–150.
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Daniels, Brian P.; Cruz-Orengo, Lillian; Pasieka, Tracy Jo; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Cooper, John A.; Doering, Tamara L. and Klein, Robyn S.
(2013).
Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier.
Journal of Neuroscience Methods, 212(1)
pp. 173–179.
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Bao Dang, Quoc; Lapergue, Bertrand; Tran-Dinh, Alexy; Diallo, Devy; Moreno, Juan-Antonio; Mazighi, Mikael; Romero, Ignacio A.; Weksler, Babette; Michel, Jean-Baptiste; Amarenco, Pierre and Meilhac, Olivier
(2013).
High-density lipoproteins limit neutrophil-induced damage to the blood–brain barrier in vitro.
Journal of Cerebral Blood Flow & Metabolism
(In Press).
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Cristante, Enrico; McArthur, Simon; Mauro, Claudio; Maggioli, Elisa; Romero, Ignacio A.; Wylezinska-Arridge, Marzena; Couraud, Pierre O.; Lopez-Tremoleda, Jordi; Christian, Helen C.; Weksler, Babette B.; Malaspina, Andrea and Solito, Egle
(2013).
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications.
Proceedings of the National Academy of Sciences, 110(3)
pp. 832–841.
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2012
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Li, Tengfei; Bourgeois, Jean-Pierre; Celli, Susanna; Glacial, Fabienne; Le Sourd, Anne-Marie; Mecheri, Salah; Weksler, Babette; Romero, Ignacio; Couraud, Pierre-Olivier; Rougeon, François and Lafaye, Pierre
(2012).
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging.
FASEB Journal
(In press).
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Kooijmans, Sander A. A.; Senyschyn, Danielle; Mezhiselvam, Muguntha M.; Morizzi, Julia; Charman, Susan A.; Weksler, Babette; Romero, Ignacio-Andres; Couraud, Pierre-Olivier and Nicolazzo, Joseph A.
(2012).
The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine.
Molecular pharmaceutics, 9(4)
pp. 883–93.
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Dickens, David; Owen, Andrew; Alfirevic, Ana; Giannoudis, Athina; Davies, Andrea; Weksler, Babette; Romero, Ignacio A; Couraud, Pierre-Olivier and Pirmohamed, Munir
(2012).
Lamotrigine is a substrate for OCT1 in brain endothelial cells.
Biochemical pharmacology, 83(6)
pp. 805–14.
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Fletcher, Nicola F.; Wilson, Garrick K.; Murray, Jacinta; Hu, Ke; Lewis, Andrew; Reynolds, Gary M.; Stamataki, Zania; Meredith, Luke W.; Rowe, Ian A.; Luo, Guangxiang; Lopez-Ramirez, Miguel A.; Baumert, Thomas F.; Weksler, Babette; Couraud, Pierre-Olivier; Kim, Kwang Sik; Romero, Ignacio A.; Jopling, Catherine; Morgello, Susan; Balfe, Peter and McKeating, Jane A.
(2012).
Hepatitis C Virus infects the endothelial cells of the blood-brain barrier.
Gastroenterology, 142(3)
634-643.e6.
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Watson, Christopher P.; Dogruel, Murat; Mihoreanu, Larisa; Begley, David J.; Weksler, Babette B.; Couraud, Pierre O.; Romero, Ignacio A. and Thomas, Sarah A.
(2012).
The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: Evidence for involvement of breast cancer resistance protein.
Brain research, 1436
pp. 111–121.
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Bintig , Willem; Begandt , Daniela; Schlingmann , Barbara; Gerhard , Linda; Pangalos , Maria; Dreyer , Lutz; Hohnjec , Natalija; Couraud , Pierre-Olivier; Romero, Ignacio A; Weksler, Babette B. and Ngezahayo , Anaclet
(2012).
Purine receptors and Ca2+ signalling in the human blood-brain barrier endothelial cell line hCMEC/D3.
Purinergic Signalling, 8(1)
pp. 71–80.
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2011
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Shen, Weiyong; Li, Shiying; Chung, Sook Hyun; Zhu, Ling; Stayt, Jason; Su, Tao; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette and Gillies, Mark C.
(2011).
Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium.
European Journal of Cell Biology, 90(4)
pp. 323–332.
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Chaitanya, Ganta V.; Cromer, Walter E.; Wells, Shannon R.; Jennings, Merilyn H.; Couraud, P. Oliver; Romero, Ignacio A; Weksler, Babette; Erdreich-Epstein, Anat; Mathis, James Michael; Minagar, Alireza and Alexander, J. Steven
(2011).
Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro.
Journal of Neuroinflammation, 8(162)
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2010
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Fossati, S.; Cam, J.; Meyerson, J.; Mezhericher, E.; Romero, I. A.; Couraud, P. O.; Weksler, B. B.; Ghiso, J. and Rostagno, A.
(2010).
Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-β variants in cells composing the cerebral vessel walls.
FASEB Journal, 24(1)
pp. 229–241.
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Najbauer, Joseph; Haarmann, Axel; Deiß, Annika; Prochaska, Jürgen; Foerch, Christian; Weksler, Babette; Romero, Ignacio; Couraud, Pierre-Olivier; Stoll, Guido; Rieckmann, Peter and Buttmann, Mathias
(2010).
Evaluation of soluble junctional adhesion molecule-a as a biomarker of human brain endothelial barrier breakdown.
PLoS ONE, 5(10)
e13568.
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van Rooy, Inge; Cakir-Tascioglu, Serpil; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Storm, Gert; Hennink, Wim E.; Schiffelers, Raymond M. and Mastrobattista, Enrico
(2010).
Identification of peptide ligands for targeting to the blood-brain barrier.
Pharmaceutical Research, 27(4)
pp. 673–682.
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2009
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Ramirez, Servio H.; Potula, Raghava; Fan, Shongshan; Eidem, Tess; Papugani, Anil; Reichenbach, Nancy; Dykstra, Holly; Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre O. and Persidsky, Yuri
(2009).
Methamphetamine disrupts blood–brain barrier function by induction of oxidative stress in brain endothelial cells.
Journal of Cerebral Blood Flow and Metabolism, 29(12)
pp. 1933–1945.
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Tai, Leon M.; Reddy, P. Sreekanth; Lopez-Ramirez, M. Alejandro; Davies, Heather A.; Male, A. David K.; Loughlin, A. Jane and Romero, Ignacio A.
(2009).
Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123.
Brain Research, 1292
pp. 14–24.
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Fischer, Silvia; Nishio, Miwako; Peters, Saskia C.; Tschernatsch, Marlene; Walberer, Maureen; Weidemann, Susanne; Heidenreich, Regina; Couraud, Pierre O.; Weksler, Babette B.; Romero, Ignacio A.; Gerriets, Tibo and Preissner, Klaus T.
(2009).
Signaling mechanism of extracellular RNA in endothelial cells.
FASEB Journal, 23(7)
pp. 2100–2109.
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Coureuil, Mathieu; Mikaty, Guillain; Miller, Florence; Lécuyer, Hervé; Bernard, Christine; Bourdoulous, Sandrine; Duménil, Guillaume; Mège, René-Marc; Weksler, Babette B.; Romero, Ignacio A.; Couraud, Pierre Olivier and Nassif, Xavier
(2009).
Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.
Science, 325(5936)
pp. 83–87.
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Hurst, Louise A.; Bunning, Rowena A.D.; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette B.; Sharrack, Basil and Woodroofe, M. Nicola
(2009).
Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment.
Journal of Neuroimmunology, 210(1-2)
pp. 108–112.
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Vukic, Vanja; Callaghan, Debbie; Walker, David; Lue, Lih-Fen; Liu, Qing Yan; Couraud, Pierre-Oliver; Romero, Ignacio A.; Weksler, Babette; Stanimirovic, Danica B. and Zhang, Wandong
(2009).
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.
Neurobiology of Disease, 34(1)
pp. 95–106.
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Zastre, Jason A.; Chan, Gary N. Y.; Ronaldson, Patrick T.; Ramaswamy, Manisha; Couraud, Pierre O.; Romero, Ignacio A.; Weksler, Babette; Bendayan, Moise and Bendayan, Reina
(2009).
Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line.
Journal of Neuroscience Research, 87(4)
pp. 1023–1036.
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Dauchy, Sandrine; Miller, Florence; Couraud, Pierre-Olivier; Weaver, Richard, J.; Weksler, Babette; Romero, Ignacio A.; Scherrmann, Jean-Michel; De Waziers, Isabelle and Decleves, Xavier
(2009).
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.
Biochemical Pharmacology, 77(5)
pp. 897–909.
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Bahbouhi, Bouchaib; Berthelot, Laureline; Pettré, Ségolène; Michel, Laure; Wiertlewski, Sandrine; Weksler, Babette; Romero, Ignacio A.; Miller, Florence; Couraud, Pierre-Olivier; Brouard, Sophie; Laplaud, David-Axel and Soulillou, Jean-Paul
(2009).
Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line.
Journal of Leukocyte Biology, 86(5)
pp. 1049–1063.
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2008
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Poller, Birk; Gutmann, Heike; Krahenbuhl, Stephan; Weksler, Babette; Romero, Ignacio A.; Couraud, Pierre-Olivier; Tuffin, Gerald; Drewe, Jürgen and Huwyler, Jörg
(2008).
The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies.
Journal of Neurochemistry, 107(5)
pp. 1358–1368.
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Afonso, Philippe V.; Ozden, Simona; Cumont, Marie-Christine; Seilhean, Danielle; Cartier, Luis; Rezaie, Payam; Mason, Sarah; Lambert, Sophie; Huerre, Michel; Gessain, Antoine; Couraud, Pierre-Olivier; Pique, Claudine; Ceccaldi, Pierre-Emmanuel and Romero, Ignacio A.
(2008).
Alteration of blood–brain barrier integrity by retroviral infection.
PLoS Pathogens, 4(11)
pp. 1–11.
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Wilhelm, Imola; Nagyoszi, Péter; Farkas, Attila E.; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Fazakas, Csilla; Dung, Ngo Thi Khue; Bottka, Sándor; Bauer, Hannelore; Bauer, Hans-Christian and Krizbai, István A.
(2008).
Hyperosmotic stress induces axl activation and cleavage in cerebral endothelial cells.
Journal of Neurochemistry, 107(1)
pp. 116–126.
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Lim, Joseph C.; Kania, Katarzyna D.; Wijesuriya, Hasini; Chawla, Sangeeta; Sethi, Jaswinder K.; Pulaski, Lukasz; Romero, Ignacio A.; Couraud, Pierre O.; Weksler, Babette B.; Hladky, Stephen B. and Barrand, Margery A.
(2008).
Activation of β-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells.
Journal of Neurochemistry, 106(4)
pp. 1855–1865.
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2007
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Schreibelt, G.; Kooij, G.; Reijerkerk, A.; van Doorn, R.; Gringhuis, S.I.; van der Poll, S.M.A.; Weksler, B.B.; Romero, Ignacio A; Couraud, P.O.; Piontek, J.; Blasig, I.E.; Dijkstra, Christine D.; Ronken, E. and de Vries, H.E.
(2007).
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling.
FASEB Journal, 21(13)
pp. 3666–3676.
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Wilhelm, Imola; Farkas, Attila E.; Nagyoszi, Peter; Varo, Gyorgy; Balint, Zoltan; Vegh, Gergely A.; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette and Krizbai, Istvan A.
(2007).
Regulation of cerebral endothelial cell morphology by extracellular calcium.
Physics in medicine and biology, 52(20)
pp. 6261–6274.
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Afonso, P.V.; Ozden, S.; Prevost, M.C.; Schmitt, C.; Seilhan, D.; Weksler, B.B.; Couraud, P.O.; Gessain, A.; Romero, I.A. and Ceccaldi, P.E.
(2007).
Human Blood Brain Barrier Disruption by Retroviral Infected Lymphocytes: Role of Myosin Light Chain Kinase in Endothelial Tight-Junction Disorganization.
Journal of Immunology, 179(4)
pp. 2576–2583.
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2006
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Couraud, P.O.; Romero, I.A. and Weksler, B.B.
(2006).
Human Blood Brain Barrier Model.
INSERM; Cornell University; Couraud, P.O.; Romero, I.A.; Weksler, B.B.,
WO/2006/056879.
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2005
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Weksler, B.B.; Subileau, E.A.; Perriere, N.; Charneau, P.; Holloway, K.; Leveque, M.; Tricoire-Leignel, H.; Nicotra, A.; Bourdolos, S.; Tourowski, P.; Male, D.K.; Roux, F.; Greenwood, J.; Romero, I.A. and Couraud, P.O.
(2005).
Blood-brain barrier-specific properties of a human adult brain endothelial cell line.
FASEB Journal, 19(13)
pp. 1872–1874.
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2004
2003
2002
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Romero, Ignacio A.; Hazan, Uriel; Cancello, Raffaella; Valente, Susana; Perrin, Virginie; Mariot, Virginie; Dumonceaux, Julie; Cindy C., Gerhardt; Strosberg, A. Donny; Courard, Pierre-Olivier and Pietri-Rouxel, France
(2002).
Human adipose cells express CD4, CXCR4, and CCR5 receptors: a new target cell type for the immunodeficiency virus-1?
FASEB Journal, 16(8)
pp. 1254–1256.
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2001
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Amos, Claire; Romero, Ignacio A.; Schulze, Charlotte; Rousell, Jonathan; Pearson, Jeremy D.; Greenwood, John and Adamson, Peter
(2001).
Cross-linking of brain endothelial intercellular adhesion molecule (ICAM)-1 induces association of ICAM-1 with detergent-insoluble cytoskeletal fraction.
Arteriosclerosis, Thrombosis, and Vascular Biology, 21
pp. 810–816.
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This list was generated on Sat May 18 22:31:27 2013 BST.
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