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Items Authored or Edited by Jane Loughlin

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Number of items: 43.

Journal Article

East, Emma; Johns, Noemie; Georgiou, Melanie; Golding, Jon; Loughlin, Jane; Kingham, Paul and Phillips, James (2013). A 3D in vitro model reveals differences in the astrocyte response elicited by potential stem cell therapies for CNS injury. Regenerative Medicine, 8(6) pp. 739–746. file

Georgiou, Melanie; Bunting, Stephen C. J.; Davies, Heather A.; Loughlin, Alison J.; Golding, Jonathan P. and Phillips, James B. (2013). Engineered neural tissue for peripheral nerve repair. Biomaterials, 34(30) pp. 7335–7343. file

Daya, Sandeep; Davies, Heather; Colyer, Frances; Tuffnell, Joshua; Loughlin, Jane and MacQueen, Hilary (2013). Fuelling an immune response: an ultrastructural study of immune-stimulated lymph nodes. Applied Cell Biology, 2(1) file

Tai, Leon M.; Reddy, P. Sreekanth; Lopez-Ramirez, M. Alejandro; Davies, Heather A.; Male, A. David K.; Loughlin, A. Jane and Romero, Ignacio A. (2009). Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123. Brain Research, 1292 pp. 14–24. file

Tai, Leon M.; Loughlin, A. Jane; Male, David K. and Romero, Ignacio A. (2009). P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-β. Journal of Cerebral Blood Flow and Metabolism, 29(6) pp. 1079–1083.

Loughlin, Jane; East, Emma; Golding, Jon and Phillips, James (2009). Developing a 3D culture model of CNS myelination. Glia, 57(S13) S119. file

Maru, Seema V.; Holloway, Karen A.; Flynn, Geraldine; Lancashire, Christine L.; Loughlin, A. Jane; Male, David K. and Romero, Ignacio A. (2008). Chemokine production and chemokine receptor expression by human glioma cells: Role of CXCL10 in tumour cell proliferation. Journal of Neuroimmunology, 199(1-2) pp. 35–45.

Daya, Sandeep; Loughlin, Alison J. and MacQueen, Hilary A. (2007). Culture and differentiation of preadipocytes in two-dimensional and three-dimensional in vitro systems. Differentiation, 75(5) pp. 360–370.

Flynn, Geraldine; Maru, Seema; Loughlin, Jane; Romero, Ignacio A. and Male, David (2003). Regulation of chemokine receptor expression in human microglia and astrocytes. Journal of Neuroimmunology, 136(1-2) pp. 84–93.

Williams, Daniel D.; Price, Nigel T.; Loughlin, A. Jane and Proud, Christopher G. (2001). Characterization of the Mammalian Initiation Factor eIF2B Complex as a GDP Dissociation Stimulator Protein. Journal of Biological Chemistry, 276(27) pp. 24697–24703.

Paulin, Fiona E.M.; Campbell, Linda E.; O'Brien, Kirsty; Loughlin, Jane and Proud, Christopher G. (2001). Eukaryotic translation initiation factor 5 (eIF5) acts as a classical GTPase-activator protein. Current Biology, 11(1) pp. 55–59.

Welsh, Gavin I.; Miller, Christa M.; Loughlin, Jane A.; Price, Nigel T. and Proud, Christopher G. (1998). Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Letters, 421(2) pp. 125–130.

Loughlin, A. J.; Copelman, C. A.; Hall, A.; Armer, T.; Young, B. C.; Landon, D. N. and Cuzner, M. L. (1997). Myelination and remyelination of aggregate rat brain cell cultures enriched with macrophages. Journal of neuroscience research, 47(4) pp. 384–392.

Cuzner, M. L.; Gveric, D.; Strand, C.; Loughlin, Jane; Paemen, L.; Opdenakker, G. and Newcombe, J. (1996). The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution. Journal of Neuropathology and Experimental Neurology, 55(12) pp. 1194–1204.

Loughlin, A. J. and Woodroofe, M. N. (1996). Inhibitory effect of interferon-gamma on LPS-induced interleukin 1 beta production by isolated adult rat brain microglia. Neurochemistry International, 29(1) pp. 77–82.

Loughlin, A. J.; Woodroofe, M. N.; Cuzner, M. L.; Honegger, P.; Comte, V. and Matthieu, J. M. (1994). Myelin basic protein content of aggregating rat brain cell cultures treated with cytokines and/or demyelinating antibody: effects of macrophage enrichment. Journal of neuroscience research, 37(5) pp. 647–653.

Cuzner, M. L.; Loughlin, A. J.; Mosley, K. and Woodroofe, M. N. (1994). The role of microglia macrophages in the processes of inflammatory demyelination and remyelination. Neuropathology and Applied Neurobiology, 20(2) pp. 200–201.

Loughlin, A. J.; Woodroofe, M. N. and Cuzner, M. L. (1993). Modulation of interferon-gamma-induced major histocompatibility complex class II and Fc receptor expression on isolated microglia by transforming growth factor-beta 1, interleukin-4, noradrenaline and glucocorticoids. Immunology, 79(1) pp. 125–130.

Loughlin, A. J.; Woodroofe, M. N. and Cuzner, M. L. (1992). Regulation of Fc receptor and major histocompatibility complex antigen expression on isolated rat microglia by tumour necrosis factor, interleukin-1 and lipopolysaccharide: effects on interferon-gamma induced activation. Immunology, 75(1) pp. 170–175.

Woodroofe, M. N.; Sarna, G. S.; Wadhwa, M.; Hayes, G. M.; Loughlin, A. J.; Tinker, A. and Cuzner, M. L. (1991). Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production. Journal of neuroimmunology, 33(3) pp. 227–236.

Conference Item

O'Rourke, Caitriona; Loughlin, Jane; Drake, Rosemary and Phillips, James (2014). Development of stabilised aligned CNS co-culture technology to model the behaviour of a range of neural cell types. In: 3D Cell Culture 2014, 25-27 June 2014, Freiburg Germany. file

Daya, Sandeep; Davies, Heather; Colyer, Frances; Tuffnell, Joshua; Loughlin, Jane and MacQueen, Hilary (2013). Adipocytes: a role in immunological memory? In: 40th UK Adipose Tissue Discussion Group and BHF Centre for Research Excellence Adipose Tissue Workshop, 12-13 December 2013, Edinburgh, UK.

Georgiou, Melanie; Golding, Jon; Loughlin, Jane and Phillips, James (2013). Fabrication of an endoneurium using engineered neural tissue within a peripheral nerve repair conduit. In: Tissue Engineering and Regenerative Medicine International Society - EU Meeting, 17-20 June 2013, Istanbul, Turkey. file

O'Rourke, Caitriona; Loughlin, A. J.; Drake, Rosemary and Phillips, J. B. (2013). A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies. In: BNA Festival of Neuroscience, 07-10 April 2013, London. file

O'Rourke, C.; Loughlin, J.; Drake, R. and Phillips, J. B. (2012). Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro. In: Neuroscience 2012, 13 - 17 October 2012, New Orleans.

Georgiou, Melanie; Bunting, Stephen; Golding, Jon; Loughlin, Jane and Phillips, James (2012). A living replacement tissue for peripheral nerve that can enhance regeneration in vitro and in vivo. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Vienna, Austria.

Georgiou, Melanie; Kingham, Paul; Bunting, Stephen; Golding, Jon; Loughlin, Jane and Phillips, James (2012). A nerve repair conduit containing differentiated adipose-derived stem cells within engineered neural tissue can support and guide neuronal growth in vitro and in vivo. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Vienna, Austria.

O'Rourke, Caitriona; Loughlin, Jane; Drake, Rosemary and Phillips, James (2012). Optimising glial cell alignment in 3D culture to facilitate the development of neural tissue models for CNS research. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Austria, Vienna.

Osei, E. T.; Evans, L.; Phillips, J. B. and Loughlin, A. J. (2012). Developing a 3D co-culture model to simulate perinatal hypoxic-ischaemic brain injury in preterm infants. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK.

Johns, N.; East, E.; Golding, J. P.; Loughlin, A. J. and Phillips, J. B. (2012). Astrocytes expressing GFP in 3D collagen gels provide an effective model for screening the glial response to potential CNS cell therapies. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK. file

O'Rourke, C. M.; Loughlin, A. J.; Drake, R. and Phillips, J. B. (2012). Defining glial cell self-alignment parameters for 3D CNS tissue models. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK. file

Georgiou, M.; Loughlin, J.; Golding, J. P.; Kingham, P. J. and Phillips, J. B. (2012). Engineered neural tissue with aligned Schwann cells supports neuronal regeneration in vivo and can be assembled using differentiated adipose-derived stem cells. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK. file

Georgiou, Melanie; Kingham, Paul; Golding, Jon; Loughlin, Jane and Phillips, James (2012). Engineered neural tissue with columns of aligned Schwann cell-like cells from differentiated adipose-derived stem cells can support and guide neuronal growth in vitro. In: 3rd International Conference on Stem Cell Engineering "Designing Cellular Therapies", 29 April - 02 May 2012, Seattle, US.

Phillips, J. and Loughlin, J. (2011). Monitoring glial cell behaviour and neuron-glial interactions in 3D hydrogel and aggregate culture systems. In: 10th European Meeting on Glial Cells in Health and Disease, 13-17 September 2011, Prague, Czech Republic.

Georgiou, M.; East, E.; Loughlin, J.; Golding, J. and Phillips, J. (2011). Aligned Schwann cells within 3D tissue-like gels provide guidance to regenerating neurites. In: 10th European Meeting on Glial Cells in Health and Disease, 13-17 September 2011, Prague, Czech Republic.

Georgiou, Melanie; Loughlin, Jane; Golding, Jon and Phillips, James (2011). Aligned cellular and acellular collagen guidance substrates for peripheral nerve repair. In: Tissue and Cell Engineering Society, 19 - 21 July 2011, Leeds. file

Georgiou, M.; East, E.; Loughlin, A. J.; Golding, J. P. and Phillips, J. B. (2011). A tissue engineered collagen conduit containing columns of aligned Schwann cells supports neuronal regeneration in vitro. In: 2011 PNS Biennial Meeting of the Peripheral Nerve Society, 25-29 June 2011, Potomac, Maryland, US.

Georgiou, M.; East, E.; Loughlin, J.; Golding, J.P. and Phillips, J.B. (2010). Schwann cells in collagen gels survive plastic compression and maintain their alignment: development of a cellular biomaterial for peripheral nerve repair. In: Tissue and Cell Engineering Society, 28-30th July, Manchester, U.K..

East, E.; Georgiou, M.; Loughlin, A.J.; Golding, J.P. and Phillips, J.B. (2010). Plastic compression of aligned cellular collagen gels for nervous system repair. In: Tissue Engineering and Regenerative Medicine International Society - EU Meeting, 13-17th June, Galway, Ireland.

Daya, Sandeep; Loughlin, Jane and MacQueen, Hilary (2009). Three-dimensional adipocyte cultures and co-cultures to study tissue interactions. In: NC3Rs/BBSRC Symposium Tissue Engineering: a new dimension to animal replacement, 2-3 April 2009, Royal College of Surgeons, London UK.

Daya, S.; Loughlin, J. and MacQueen, H. (2006). Development of a 3D coculture system to study adipocyte and lymph node cell interactions. In: Tissue and cell engineering systems meeting 2006, 3-4 July 2006, Sheffield, UK. file

Daya, Sandeep; Loughlin, Jane and MacQueen, Hilary (2005). Development of a three-dimensional co-culture system to study adipocyte and lymph node cell interactions. In: British Society for Immunology Winter meeting 2005, 6-9 Dec 2005, Harrogate, UK.

Patent

MacQueen, Hilary; Loughlin, Jane and Daya, Sandeep (2007). Three-dimensional cell culture. The Open University, PCT/GB2007/050161.

This list was generated on Mon Jul 28 22:48:28 2014 BST.

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