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Near IR-emitting DNA-probes exploiting stepwise energy transfer processes

Bruce, James; Borbas, K. Eszter and Bodi, Andras (2007). Near IR-emitting DNA-probes exploiting stepwise energy transfer processes. Dalton Transactions, 38 pp. 4352–4358.

DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1039/b708940f
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Abstract

The synthesis and characterisation of two new cyclen-based near IR-emitting lanthanide complexes are reported; the lanthanides are sensitised by rhodamine, which in turn is excited by energy transfer from a coumarin 2 moiety. Double stranded DNA selectively switches one of the two energy transfer processes off, enabling luminescent Q1 DNA-sensing in the near IR region. The regioselective di-alkylation of the cyclen scaffold is explained with the help of DFT calculations.

Item Type: Journal Article
ISSN: 0300-9246
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Biomedical Research Network (BRN)
Item ID: 8934
Depositing User: James Bruce
Date Deposited: 20 Aug 2007
Last Modified: 07 Mar 2014 13:46
URI: http://oro.open.ac.uk/id/eprint/8934
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