Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, 103 pp. 165–173.
This report covers some highlights in chemical genetics published during 2006. Significant advances have been made in the development of diversity-oriented synthesis to make new molecules with natural product-like skeletal diversity. The use of small molecules to interact with specific pathways in order to understand biological mechanisms and to identify new drug targets is also a main focus of this report.
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