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Melatonin Levels and Low‐Frequency Magnetic Fields in Humans and Rats: New Insights From a Bayesian Logistic Regression

Bouché, Nicolas F. and McConway, Kevin (2019). Melatonin Levels and Low‐Frequency Magnetic Fields in Humans and Rats: New Insights From a Bayesian Logistic Regression. Bioelectromagnetics (Early Access).

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DOI (Digital Object Identifier) Link: https://doi.org/10.1002/bem.22218
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Abstract

The present analysis revisits the impact of extremely low‐frequency magnetic fields (ELF‐MF) on melatonin (MLT) levels in human and rat subjects using both a parametric and non‐parametric approach. In this analysis, we use 62 studies from review articles. The parametric approach consists of a Bayesian logistic regression (LR) analysis and the non‐parametric approach consists of a Support Vector analysis, both of which are robust against spurious/false results. Both approaches reveal a unique well‐ordered pattern, and show that human and rat studies are consistent with each other once the MF strength is restricted to cover the same range (with B ≲ 50 μT). In addition, the data reveal that chronic exposure (longer than ∼22 days) to ELF‐MF appears to decrease MLT levels only when the MF strength is below a threshold of ~30 μT, i.e., when the man‐made ELF‐MF intensity is below that of the static geomagnetic field. Studies reporting an association between ELF‐MF and changes to MLT levels and the opposite (no association with ELF‐MF) can be reconciled under a single framework.

Item Type: Journal Item
Copyright Holders: 2019 Bioelectromagnetics Society
ISSN: 1521-186X
Keywords: tatistics: Bayesian; epidemiology; non‐ionizing radiation; electro‐magneticfield(EMF); melatonin
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Mathematics and Statistics
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Item ID: 67194
SWORD Depositor: Jisc Publications-Router
Depositing User: Jisc Publications-Router
Date Deposited: 09 Oct 2019 14:03
Last Modified: 11 Nov 2019 02:14
URI: http://oro.open.ac.uk/id/eprint/67194
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