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Sex differences in pregnenolone sulphate in the chick brain after training

Migues, Paola V.; Johnston, Amy N. B. and Rose, Steven P.R. (2005). Sex differences in pregnenolone sulphate in the chick brain after training. NeuroReport, 16(6) pp. 537–540.

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Pregnenolone and pregnenolone sulphate are potent memory enhancers when administered to rodents prior to various learning and memory paradigms. Here, we show that training on a passive avoidance task results in the increased concentration of pregnenolone sulphate in the medial striatum, formerly known as lobus parolfactorius of female but not male chicks. In addition, we demonstrated potential for neuronal synthesis of pregnenolone in the day-old chick brain, including in the intermediate medial mesopallium, formerly known as intermediate medial hyperstriatum ventrale and the medial striatum. © 2005 Lippincott Williams & Wilkins.

Item Type: Journal Article
ISSN: 0959-4965
Keywords: day old chicks; memory; neurosteroids biosynthesis; inhibitor; neurons; mouse; rats
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Item ID: 6717
Depositing User: Astrid Peterkin
Date Deposited: 14 Feb 2007
Last Modified: 14 Jan 2016 16:27
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