Daya, S.; Loughlin, J. and MacQueen, H.
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We have developed a long term 3-dimensional coculture system with adipocytes and lymph node
cells for the purpose of investigating interactions between these cells in vitro. Present experimental work with the culture system is aimed at introducing lymph node cells, in proportions similar to those found in intact lymph nodes, among differentiated adipocytes and observing interactions and the establishment of a spatial relationship between them. Co-cultures will be used to investigate the lymph node adipocyte interactions following immune stimulation (lipopolysaccharide treatment) measuring production of inflammatory mediators (cytokines) and lipolytic activity.
|Item Type:||Conference Item|
|Keywords:||3D culture; adipocyte; lymph node; cytokine|
|Academic Unit/Department:||Science > Life, Health and Chemical Sciences
|Interdisciplinary Research Centre:||Biomedical Research Network (BRN)|
|Depositing User:||Hilary MacQueen|
|Date Deposited:||31 Jan 2007|
|Last Modified:||15 Jan 2016 16:46|
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