An alkylation route to carbo- and heteroaromatic amino acids

Jones, Raymond C.F.; Berthelot, Didier J.C. and Iley, James N. (2007). An alkylation route to carbo- and heteroaromatic amino acids. Arkivoc(11) pp. 73–84.

DOI: https://doi.org/10.3998/ark.5550190.0008.b07

URL: http://www.arkat-usa.org/get-file/23153/

Abstract

Amino acids carrying aromatic carbo- and heterocycles in the side chain, such as naphthyl-, biphenyl- and pyridylalanines, have been prepared by alkylation of a glycine enolate with a haloalkyl carbocycle or heterocycle, with enantiomeric excess up to 87% using the ephedrine amide protocol.

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About

  • Item ORO ID
  • 5974
  • Item Type
  • Journal Item
  • ISSN
  • 1551-7012
  • Extra Information
  • for the Heterocyclic Group on their 40th Anniversary
  • Keywords
  • amino acid; non-proteinogenic; ephedrine glycinamide; glycine enolate; pyridylalanine
  • Academic Unit or School
  • Other Departments > Business Development Unit
    Other Departments
  • Copyright Holders
  • © 2007 ARKAT USA, Inc.
  • Depositing User
  • James Iley
CORE (COnnecting REpositories)

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