Jones, Raymond C.F.; Berthelot, Didier J.C. and Iley, James N.
An alkylation route to carbo- and heteroaromatic amino acids.
Arkivoc(11) pp. 73–84.
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Amino acids carrying aromatic carbo- and heterocycles in the side chain, such as naphthyl-, biphenyl- and pyridylalanines, have been prepared by alkylation of a glycine enolate with a haloalkyl carbocycle or heterocycle, with enantiomeric excess up to 87% using the ephedrine amide protocol.
||2007 ARKAT USA, Inc.
||for the Heterocyclic Group on their 40th Anniversary
||amino acid; non-proteinogenic; ephedrine glycinamide; glycine enolate; pyridylalanine
||04 Dec 2006
||24 Feb 2016 20:29
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