The Role Of p14ARF In Familial And Sporadic Melanoma

Mistry, Sushilaben Harkisandas (2004). The Role Of p14ARF In Familial And Sporadic Melanoma. PhD thesis University of Leeds.

Viewing alternatives

Item Actions



  • Item ORO ID
  • 59023
  • Item Type
  • PhD Thesis
  • Extra Information
  • The author was the first to: comprehensively screen for deletions on chromosome 9p in melanoma families and in sporadic melanomas (at a time when it was difficult for detect deletions and loss of heterozygosity, LOH); to identify p14ARF [CDKN2A-ARF gene (exon 1β)] as a tumour suppressor gene; identify the MTAP to KIAA1 gene region as important in melanoma aetiology and a candidate locus for the location of a tumour suppressor gene; and contributed to being the first to identify that introns are important in disease with the detection of a splicing variant (IVS2-105) in melanoma families.
  • Keywords
  • chromosomes; melanoma; tumours; cancer
  • Academic Unit or School
  • Other Departments > Other Departments
  • Research Group
  • Cancer Research Group
  • Copyright Holders
  • © 2004 The Author
  • Depositing User
  • Sushila Rigas