The Role Of p14ARF In Familial And Sporadic Melanoma

Mistry, Sushilaben Harkisandas (2004). The Role Of p14ARF In Familial And Sporadic Melanoma. PhD thesis University of Leeds.

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  • Item ORO ID
  • 59023
  • Item Type
  • PhD Thesis
  • Extra Information
  • The author was the first to: comprehensively screen for deletions on chromosome 9p in melanoma families and in sporadic melanomas (at a time when it was difficult for detect deletions and loss of heterozygosity, LOH); to identify p14ARF [CDKN2A-ARF gene (exon 1β)] as a tumour suppressor gene; identify the MTAP to KIAA1 gene region as important in melanoma aetiology and a candidate locus for the location of a tumour suppressor gene; and contributed to being the first to identify that introns are important in disease with the detection of a splicing variant (IVS2-105) in melanoma families.
  • Keywords
  • chromosomes; melanoma; tumours; cancer
  • Academic Unit or School
  • Other Departments > Other Departments
  • Research Group
  • Cancer Research Group
  • Copyright Holders
  • © 2004 The Author
  • Depositing User
  • Sushila Rigas
CORE (COnnecting REpositories)

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