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Chemical Genetics

Shuker, David E.G. (2005). Chemical Genetics. Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, 101 pp. 137–147.

DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1039/b418968j
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Abstract

This review covers some of the highlights in the field of chemical genetics published during 2004. A key enabling methodology in the field is the availability of diverse libraries of small molecules provided by combinatorial
chemistry, and notable advances in this area are included. As the chemical genetic approach becomes more widely established the number of new biological pathways targeted by novel small molecules increases, and significant discoveries made during the year are summarised. Of particular note during 2004 was the publication of a series of review and commentary articles on the theme of ‘‘chemical space’’—a concept central to chemical
genetics.

Item Type: Journal Article
ISSN: 0069-3030
Keywords: chemical genetics; diversity-oriented synthesis
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Item ID: 5525
Depositing User: David Shuker
Date Deposited: 16 Oct 2006
Last Modified: 02 Dec 2010 19:54
URI: http://oro.open.ac.uk/id/eprint/5525
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