The Open UniversitySkip to content
 

Communication: Site-selective bond excision of adenine upon electron transfer

Cunha, T.; Mendes, M.; Ferreira da Silva, F.; Eden, S.; García, G. and Limão-Vieira, P. (2018). Communication: Site-selective bond excision of adenine upon electron transfer. Journal of Chemical Physics, 148(2), article no. 021101.

Full text available as:
[img]
Preview
PDF (Accepted Manuscript) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (1MB) | Preview
DOI (Digital Object Identifier) Link: https://doi.org/10.1063/1.5018401
Google Scholar: Look up in Google Scholar

Abstract

This work demonstrates that selective excision of hydrogen atoms at a particular site of the DNA base adenine can be achieved in collisions with electronegative atoms by controlling the impact energy. The result is based on analysing the time-of-flight mass spectra yields of potassium collisions with a series of labeled adenine derivatives. The production of dehydrogenated parent anions is consistent with neutral H loss either from selective breaking of C–H or N–H bonds. These unprecedented results open up a new methodology in charge transfer collisions that can initiate selective reactivity as a key process in chemical reactions that are dominant in different areas of science and technology.

Item Type: Journal Item
Copyright Holders: 2018 The Authors
ISSN: 1089-7690
Project Funding Details:
Funded Project NameProject IDFunding Body
Electron attachment to biomolecular clusters: probing the role of multiple scattering in radio-sensitivity (SP-10-088-SE)EP/J002577/1EPSRC (Engineering and Physical Sciences Research Council)
Keywords: chemical compounds; mass spectra; hydrogen; collision theories; transition state theory
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Physical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Research Group: Physics
Item ID: 52882
Depositing User: Sam Eden
Date Deposited: 12 Jan 2018 15:11
Last Modified: 12 Feb 2018 10:16
URI: http://oro.open.ac.uk/id/eprint/52882
Share this page:

Metrics

Altmetrics from Altmetric

Citations from Dimensions

Download history for this item

These details should be considered as only a guide to the number of downloads performed manually. Algorithmic methods have been applied in an attempt to remove automated downloads from the displayed statistics but no guarantee can be made as to the accuracy of the figures.

Actions (login may be required)

Policies | Disclaimer

© The Open University   contact the OU