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Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions

El Aziz, Youssef; Mehrban, Nazia; Taylor, Peter G.; Birchall, Martin A.; Bowen, James; Bassindale, Alan R.; Pitak, Mateusz B. and Coles, Simon J. (2017). Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions. RSC Advances, 7(59) pp. 37474–37477.

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DOI (Digital Object Identifier) Link: https://doi.org/10.1039/C7RA07915J
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Abstract

A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82–90%). The X-ray crystal structure revealed intra- and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc- norleucine and (ii) 3'-azido-3'-deoxythymidine.

Item Type: Journal Item
Copyright Holders: 2017 The Royal Society of Chemistry
ISSN: 2046-2069
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Faculty of Science, Technology, Engineering and Mathematics (STEM) > Engineering and Innovation
Other Departments > Vice-Chancellor's Office
Other Departments
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Item ID: 50439
Depositing User: James Bowen
Date Deposited: 10 Aug 2017 14:56
Last Modified: 21 Aug 2017 08:19
URI: http://oro.open.ac.uk/id/eprint/50439
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