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Structural lipid nanoparticles self-assembled from electrospun core–shell polymeric nanocomposites

Yu, Deng-Guang; White, Kenneth; Chatterton, Nicholas; Li, Ying; Li, Lingling and Wang, Xia (2015). Structural lipid nanoparticles self-assembled from electrospun core–shell polymeric nanocomposites. RSC Advances, 5(13) pp. 9462–9466.

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DOI (Digital Object Identifier) Link: https://doi.org/10.1039/c4ra14001j
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Abstract

Electrospun polymeric core–shell nanocomposites are exploited as templates to manipulate molecular self-assembly for preparing structural lipid nanoparticles, during which the confinement effect of fibers together with their core–shell structure, the aqueous environment and the secondary interactions, all contributed synergistically to facilitate molecular self-aggregation to produce lipid nanoparticles with a drug entrapment efficiency of 95.9% with a sustained drug release profile.

Item Type: Journal Item
Copyright Holders: 2015 The Royal Society of Chemistry
ISSN: 2046-2069
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Item ID: 43990
Depositing User: Nicholas Chatterton
Date Deposited: 17 Aug 2015 08:46
Last Modified: 02 Jul 2020 11:42
URI: http://oro.open.ac.uk/id/eprint/43990
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