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Effect of active screen plasma nitriding on the biocompatibility of UHMWPE surfaces

Kaklamani, Georgia; Mehrban, Nazia; Bowen, James; Grover, Liam M.; Dong, Hanshan and Stamboulis, Artemis (2010). Effect of active screen plasma nitriding on the biocompatibility of UHMWPE surfaces. In: 2nd International Symposium on Surface and Interface of Biomaterials, 4-6 January 2010, Hong Kong.

URL: https://www.academia.edu/9824373/Effect_of_active_...
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Abstract

Active screen plasma nitriding (ASPN) is used to chemically modify the surface of UHMWPE. This is an unexplored and new area of research. ASPN allows the homogeneous treatment of any shape or surface at low temperature; therefore, it was thought that ASPN would be an effective technique to modify organic polymer surfaces. ASPN experiments were carried out at 120 °C using a dc plasma nitriding unit with a 25% N(2) and 75% H(2) atmosphere at 2.5 mbar of pressure. UHMWPE samples treated for different time periods were characterized by nanoindentation, FTIR, XPS, interferometry and SEM. A 3T3 fibroblast cell line was used for in vitro cell culture experiments. Nanoindentation of UHMWPE showed that hardness and elastic modulus increased with ASPN treatment compared to the untreated material. FTIR spectra did not show significant differences between the untreated and treated samples; however, some changes were observed at 30 min of treatment in the range of 1500-1700 cm(-1) associated mainly with the presence of N-H groups. XPS studies showed that nitrogen was present on the surface and its amount increased with treatment time. Interferometry showed that no significant changes were observed on the surfaces after the treatment. Finally, cell culture experiments and SEM showed that fibroblasts attached and proliferated to a greater extent on the plasma-treated surfaces leading to the conclusion that ASPN surface treatment can potentially significantly improve the biocompatibility behaviour of polymeric materials

Item Type: Conference or Workshop Item
Copyright Holders: 2010 The Authors
Keywords: biomaterials; stem cells; regenerative medicine; surface chemistry; UHMWPE; plasma nitriding
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Engineering and Innovation
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Item ID: 43422
Depositing User: James Bowen
Date Deposited: 18 Jun 2015 09:46
Last Modified: 10 Nov 2016 17:18
URI: http://oro.open.ac.uk/id/eprint/43422
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