Truong, Vinh X.; Ablett, Matthew P.; Gilbert, Hamish T. J.; Bowen, James; Richardson, Stephen M.; Hoyland, Judith A. and Dove, Andrew P.
(2014).
|
PDF (Version of Record)
- Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (1MB) | Preview |
| DOI (Digital Object Identifier) Link: | https://doi.org/10.1039/c3bm60159e |
|---|---|
| Google Scholar: | Look up in Google Scholar |
Abstract
A water-soluble azide-functionalised chitosan was crosslinked with propiolic acid ester-functional poly-(ethylene glycol) using copper-free click chemistry. The resultant hydrogel materials were formed within 5–60 min at 37 °C and resulted in mechanically robust materials with tuneable properties such as swelling, mechanical strength and degradation. Importantly, the hydrogels supported mesenchymal stem cell attachment and proliferation and were also non-toxic to encapsulated cells. As such these studies indicate that the hydrogels have potential to be used as injectable biomaterials for tissue engineering.
| Item Type: | Journal Item |
|---|---|
| Copyright Holders: | 2014 The Authors |
| ISSN: | 2047-4849 |
| Academic Unit/School: | Faculty of Science, Technology, Engineering and Mathematics (STEM) > Engineering and Innovation Faculty of Science, Technology, Engineering and Mathematics (STEM) |
| Item ID: | 43157 |
| Depositing User: | James Bowen |
| Date Deposited: | 01 Jun 2015 09:32 |
| Last Modified: | 02 May 2018 14:09 |
| URI: | http://oro.open.ac.uk/id/eprint/43157 |
| Share this page: |     |
Metrics
Altmetrics from Altmetric | Citations from Dimensions |
Download history for this item
These details should be considered as only a guide to the number of downloads performed manually. Algorithmic methods have been applied in an attempt to remove automated downloads from the displayed statistics but no guarantee can be made as to the accuracy of the figures.
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)