The Open UniversitySkip to content
 

Nucleotides and oligonucleotides: mononucleotides

Narukulla, Raman and Xu, Yao-Zhong (2015). Nucleotides and oligonucleotides: mononucleotides. In: Allen, David; Tebby, John C. and Loakes, David eds. Organophosphorus Chemistry, Volume 44. Cambridge: The Royal Society of Chemistry, pp. 170–192.

Full text available as:
Full text not publicly available
Due to copyright restrictions, this file is not available for public download
DOI (Digital Object Identifier) Link: https://doi.org/10.1039/9781782622765-00170
Google Scholar: Look up in Google Scholar

Abstract

This chapter covers selected papers published in 2013 on chemical synthesis and medicinal application of modified nucleotides and oligonucleotides. Nucleotides are the building blocks of nucleic acids and play fundamental roles in biological processes. Novel synthetic methods for modified nucleotides are continuously developed and their biological potentials extensively explored. As in the previous year the chemical synthesis and medicinal exploration of modified nucleoside monophosphates and triphosphates are divided into sections relating to the nucleobase and sugar. This chapter also reviews research developments on various forms of modified nucleotides, including phosphoramidites, phosphoramidates and phosphonates, triphosphates and oligomers.

Item Type: Book Section
Copyright Holders: 2015 The Royal Society of Chemistry
ISBN: 1-78262-111-3, 978-1-78262-111-9
Keywords: nucleoside monophosphates
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Item ID: 42724
Depositing User: Yao Xu
Date Deposited: 12 May 2015 08:49
Last Modified: 15 Sep 2017 11:01
URI: http://oro.open.ac.uk/id/eprint/42724
Share this page:

Altmetrics

Actions (login may be required)

Policies | Disclaimer

© The Open University   contact the OU