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Medvedev, Nikolay; Popov, Victor; Henneberger, Christian; Kraev, Igor; Rusakov, Dmitri and Stewart, Michael
(2014).
DOI: https://doi.org/10.1098/rstb.2014.0047
Abstract
This paper examines the relationship between the morphological modality of 189 dendritic spines and the surrounding astroglia using full three dimensional reconstructions of neuropil fragments. An integrative measure of three-dimensional glial coverage confirms that thin spine PSDs are more tightly surrounded by glia. This distinction suggests that diffusion-dependent synapse–glia communication near ‘learning’ synapses (associated with thin spines) could be stronger than that near ‘memory’ synapses (associated with larger spines).
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About
- Item ORO ID
- 40717
- Item Type
- Journal Item
- ISSN
- 1471-2970
- Project Funding Details
-
Funded Project Name Project ID Funding Body The role of multi-innervated dendritic spines in memory formation in old age BB/J021687/1 BBSRC - Extra Information
- 7 pp.
- Keywords
- glia protection; synapses; thin spines
- Academic Unit or School
-
Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM) - Research Group
- Centre for Research in Computing (CRC)
- Copyright Holders
- © 2014 The Authors
- Related URLs
- Depositing User
- Michael Stewart