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Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleobase side chains

Jones, Raymond C. F.; Berthelot, Didier J.C. and Iley, James N. (2001). Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleobase side chains. Tetrahedron, 57(30) pp. 6539–6555.

DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1016/S0040-4020(01)00546-4
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Abstract

N-(2-Iodoethyl) and N-(3-iodopropyl)pyrimidines and purines undergo stereoselective conjugate radical addition with an optically active oxazolidinone acceptor to give syn adducts that can be converted into amino acids carrying pyrimidine and purine (nucleobase) side chains.

Item Type: Journal Article
ISSN: 0040-4020
Extra Information: Some of the symbols may not have transferred correctly into this bibliographic record.
Keywords: PNA; nucleobase amino acids; chimeric amino acids; nucleic acid analogues; amino acids; radical reactions
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Item ID: 4016
Depositing User: James Iley
Date Deposited: 04 Jul 2006
Last Modified: 02 Dec 2010 19:50
URI: http://oro.open.ac.uk/id/eprint/4016
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