Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleobase side chains

Jones, Raymond C. F.; Berthelot, Didier J.C. and Iley, James N. (2001). Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleobase side chains. Tetrahedron, 57(30) pp. 6539–6555.

DOI: https://doi.org/10.1016/S0040-4020(01)00546-4

Abstract

N-(2-Iodoethyl) and N-(3-iodopropyl)pyrimidines and purines undergo stereoselective conjugate radical addition with an optically active oxazolidinone acceptor to give syn adducts that can be converted into amino acids carrying pyrimidine and purine (nucleobase) side chains.

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About

  • Item ORO ID
  • 4016
  • Item Type
  • Journal Item
  • ISSN
  • 0040-4020
  • Extra Information
  • Some of the symbols may not have transferred correctly into this bibliographic record.
  • Keywords
  • PNA; nucleobase amino acids; chimeric amino acids; nucleic acid analogues; amino acids; radical reactions
  • Academic Unit or School
  • Other Departments > Other Departments
    Other Departments
  • Depositing User
  • James Iley

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