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Multi-photon and electron impact ionisation studies of reactivity in adenine–water clusters

Barc, B.; Ryszka, M.; Poully, J.-C.; Jabbour Al Maalouf, E.; el Otell, Z.; Tabet, J.; Parajuli, R.; van der Burgt, P.J.M.; Limão-Vieira, P.; Cahillane, P.; Dampc, M.; Mason, N. J. and Eden, S. (2014). Multi-photon and electron impact ionisation studies of reactivity in adenine–water clusters. International Journal of Mass Spectrometry, 365-366 pp. 194–199.

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Multi-photon ionisation (MPI) and electron impact ionisation (EII) mass spectrometry experiments have been carried out to probe unimolecular and intermolecular reactivities in hydrated adenine clusters. The effects of clustering with water on fragment ion production from adenine have been studied for the first time. While the observation of NH4+ fragments indicated the dissociation of protonated adenine, the dominant hydration effects were enhanced C4H4N4+ production and the suppression of dissociative ionisation pathways with high activation energies. These observations can be attributed to energy removal from the excited adenine radical cation via cluster dissociation. Comparisons of MPI and EII measurements provided the first experimental evidence supporting hypoxanthine formation in adenine–water clusters via theoretically predicted barrierless deamination reactions in closed shell complexes.

Item Type: Journal Item
Copyright Holders: 2014 Elsevier B.V.
ISSN: 1387-3806
Project Funding Details:
Funded Project NameProject IDFunding Body
Life Sciences Interface FellowshipEP/E039618/1EPSRC
Career Acceleration FellowshipEP/J002577/1EPSRC
Research GrantEP/L002191/1EPSRC
Marie Curie Intra-European Reintegration GrantMERGCT- 2007-207292European Commission
Extra Information: Special issue: Tilmann Mäerk
Keywords: adenine; cluster; dissociative ionisation; hypoxanthine; multi-photon ionisation; electron impact ionisation
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Physical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Research Group: Physics
Item ID: 39726
Depositing User: Miranda Callaway
Date Deposited: 18 Mar 2014 10:14
Last Modified: 30 May 2020 09:37
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