Ashraff, S; Brown, R.A. and Phillips, J.B.
Plastic compression of collagen: development and assessment of a new biomaterial in nerve repair.
European Cells and Materials, 10(2)
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Nerve reconstruction is a surgical challenge. Current neural conduits provide sub-optimal clinical results. We have developed a device from a composite material comprising a fibronectin core and a collagen outer layer, using collagen made by a new technique called plastic compression. This collagen element has the strength to improve the mechanical properties of nerve repair devices which is an important design consideration. Preliminary studies have been performed to assess the suitability of the new collagen material for use in nerve repair conduits.
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