Investigating the effect of photodynamic therapy on nerves using tissue engineered culture models

Wright, K.E.; Liniker, E; MacRobert, A.J.; Brown, R.A.; Saffrey, M.J. and Phillips, J.B. (2006). Investigating the effect of photodynamic therapy on nerves using tissue engineered culture models. In: Tissue & Cell Engineering Society 2006, 3-4 Jul 2006, Sheffield, UK.

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Abstract

Introduction: Photodynamic therapy (PDT) shows potential as an effective treatment for prostate cancer. Clinical observations indicate that this approach causes fewer nerve damage related side-effects than conventional treatments. The aim here is to investigate the effect of PDT on nerve tissue using engineered 3-dimensional cell culture models. Initial experiments focussed on establishing photosensitiser localisation in neurones and Schwann cells, then developing a model for simulating nerve PDT in culture.

Item Type:	Conference Item
Academic Unit/Department:	Science > Life, Health and Chemical Sciences
Item ID:	3920
Depositing User:	James Phillips
Date Deposited:	11 Aug 2006
Last Modified:	04 Dec 2010 12:59
URI:	http://oro.open.ac.uk/id/eprint/3920

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