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Synthetic chemistry of base-modified DNA and their biological applications

Xu, Yao-Zhong (2002). Synthetic chemistry of base-modified DNA and their biological applications. In: Loakes, David ed. Modified Nulceoside, Synthesis and Applications. Kerala, India: Research Signpost, pp. 1–16.

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Synthetic chemistry of base-modified DNA has provided a powerful tool for studying DNA-related subjects, in particular for understanding DNA damage and repair. This chapter first introduces basic concepts of DNA synthetic chemistry, and then reviews various approaches to chemical synthesis of base-modified DNA. It also presents the commonly used methods for purification and verification, illustrates applications of the synthetic base-modified oligomers and discusses the potentials of the synthetic chemistry.

Item Type: Book Chapter
ISBN: 81-7736-121-X, 978-81-7736-121-6
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Item ID: 3850
Depositing User: Yao Xu
Date Deposited: 21 Mar 2007
Last Modified: 14 Jan 2016 15:57
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