The Open UniversitySkip to content
 

Synthetic chemistry of base-modified DNA and their biological applications

Xu, Yao-Zhong (2002). Synthetic chemistry of base-modified DNA and their biological applications. In: Loakes, David ed. Modified Nulceoside, Synthesis and Applications. Kerala, India: Research Signpost, pp. 1–16.

Google Scholar: Look up in Google Scholar

Abstract

Synthetic chemistry of base-modified DNA has provided a powerful tool for studying DNA-related subjects, in particular for understanding DNA damage and repair. This chapter first introduces basic concepts of DNA synthetic chemistry, and then reviews various approaches to chemical synthesis of base-modified DNA. It also presents the commonly used methods for purification and verification, illustrates applications of the synthetic base-modified oligomers and discusses the potentials of the synthetic chemistry.

Item Type: Book Chapter
ISBN: 81-7736-121-X, 978-81-7736-121-6
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Item ID: 3850
Depositing User: Yao Xu
Date Deposited: 21 Mar 2007
Last Modified: 10 Mar 2014 09:32
URI: http://oro.open.ac.uk/id/eprint/3850
Share this page:

Actions (login may be required)

View Item
Report issue / request change

Policies | Disclaimer

© The Open University   + 44 (0)870 333 4340   general-enquiries@open.ac.uk