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Bootman, Martin D.; Collins, Tony J.; Peppiatt, Claire M.; Prothero, Larissa S.; MacKenzie, Lauren; De Smet, Patrick; Travers, Marianne; Tovey, Stephen C.; Seo, Jeong T.; Berridge, Michael J.; Ciccolini, Francesca and Lipp, Peter
(2001).
DOI: https://doi.org/10.1006/scdb.2000.0211
Abstract
Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation. The ability of a simple ion such as Ca2+ to play a pivotal role in cell biology results from the facility that cells have to shape Ca2+ signals in the dimensions of space, time and amplitude. To generate the variety of observed Ca2+ signals, different cell types employ components selected from a Ca2+ signalling 'toolkit', which comprizes an array of signalling, homeostatic and sensory mechanisms. By mixing and matching components from the toolkit, cells can obtain Ca2+ signals that suit their physiology.
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- Item ORO ID
- 34981
- Item Type
- Journal Item
- ISSN
- 1096-3634
- Keywords
- calcium; signalling; homeostasis; channel
- Academic Unit or School
-
Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM) - Copyright Holders
- © 2001 Academic Press
- Depositing User
- Martin Bootman
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)