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Cell signalling: IP3 receptors channel calcium into cell death

Hanson, C. Jane; Bootman, Martin D. and Roderick, H. Llewelyn (2004). Cell signalling: IP3 receptors channel calcium into cell death. Current Biology, 14(21) R933-R935.

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DOI (Digital Object Identifier) Link: https://doi.org/10.1016/j.cub.2004.10.019
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Abstract

There is substantial evidence that Ca2+ fluxes occur during most forms of apoptosis, and that inhibiting such fluxes protects cells from death. IP3 receptors – ligand-gated channels that release Ca2+ from intracellular stores – are emerging as key sites for regulation by pro- and anti-apoptotic factors.

Item Type: Journal Item
Copyright Holders: 2004 Elsevier Ltd
ISSN: 1879-0445
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Related URLs:
Item ID: 34916
Depositing User: Martin Bootman
Date Deposited: 26 Apr 2013 09:02
Last Modified: 09 Dec 2018 01:36
URI: http://oro.open.ac.uk/id/eprint/34916
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