The Open UniversitySkip to content
 

Sizing gaseous emboli using doppler embolic signal intensity

Banahan, Caroline; Hague, James P.; Evans, David H.; Patel, Rizwan; Ramnarine, Kumar V. and Chung, Emma M.L. (2012). Sizing gaseous emboli using doppler embolic signal intensity. Ultrasound in Medicine & Biology, 38(5) pp. 824–833.

DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1016/j.ultrasmedbio.2012.01.008
Google Scholar: Look up in Google Scholar

Abstract

Extension of transcranial Doppler embolus detection to estimation of bubble size has historically been hindered by difficulties in applying scattering theory to the interpretation of clinical data. This article presents a simplified approach to the sizing of air emboli based on analysis of Doppler embolic signal intensity, by using an approximation to the full scattering theory that can be solved to estimate embolus size. Tests using simulated emboli show that our algorithm is theoretically capable of sizing 90% of “emboli” to within 10% of their true radius. In vitro tests show that 69% of emboli can be sized to within 20% of their true value under ideal conditions, which reduces to 30% of emboli if the beam and vessel are severely misaligned. Our results demonstrate that estimation of bubble size during clinical monitoring could be used to distinguish benign microbubbles from potentially harmful macrobubbles during intraoperative clinical monitoring.

Item Type: Journal Article
Copyright Holders: 2012 World Federation for Ultrasound in Medicine & Biology
ISSN: 0301-5629
Keywords: embolus detection; transcranial Doppler ultrasound; gaseous emboli
Academic Unit/Department: Science > Physical Sciences
Interdisciplinary Research Centre: Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Biomedical Research Network (BRN)
Item ID: 33216
Depositing User: James Hague
Date Deposited: 16 Mar 2012 09:15
Last Modified: 07 Mar 2014 13:48
URI: http://oro.open.ac.uk/id/eprint/33216
Share this page:

Altmetrics

Scopus Citations

Actions (login may be required)

View Item
Report issue / request change

Policies | Disclaimer

© The Open University   + 44 (0)870 333 4340   general-enquiries@open.ac.uk