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Longitudinal trajectories of awareness in early-stage dementia

Clare, Linda; Nelis, Sharon M.; Martyr, Anthony; Whitaker, Christopher J.; Marková, Ivana S.; Roth, Ilona; Woods, Robert T. and Morris, Robin G. (2012). Longitudinal trajectories of awareness in early-stage dementia. Alzheimer Disease and Associated Disorders, 26(2) 140 -147.

DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1097/WAD.0b013e31822c55c4
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Abstract

Although it is often assumed that awareness decreases as dementia severity increases, there is limited evidence regarding changes in awareness over time. We examined awareness in 101 individuals with early-stage dementia (PwD) and their carers; 66 were reassessed after 12 months and 51 were seen again at 20 months. Awareness was assessed in relation to memory, everyday activities, and socio-emotional functioning using discrepancies between PwD and carer ratings on parallel questionnaires. PwD completed neuropsychological tests and measures of mood and quality of life. Carers completed measures of mood and stress. At initial assessment, discrepancies were greatest for activities of daily living, moderate for memory, and least pronounced for socio-emotional functioning. Discrepancy scores did not change over time. PwD self-ratings indicated perceived poorer functioning in everyday activities over time, but no change for memory and socio-emotional functioning. Carer ratings indicated perceived decline in everyday activities and socio-emotional functioning, but no change for memory. PwD declined in neuropsychological functioning, but self-ratings of depression, anxiety, and quality of life remained stable over time. Carer mood and stress levels also remained stable. At least in the earlier stages of dementia, it should not be assumed that awareness will inevitably decrease as dementia progresses.

Item Type: Journal Article
Copyright Holders: 2011 Lippincott Williams and Wilkins
ISSN: 0893-0341
Project Funding Details:
Funded Project NameProject IDFunding Body
Not SetNot SetESRC
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Related URLs:
Item ID: 30878
Depositing User: Ilona Roth
Date Deposited: 22 Dec 2011 11:46
Last Modified: 19 Mar 2014 16:01
URI: http://oro.open.ac.uk/id/eprint/30878
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